Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TACR1 | P25103 | 1/20 | 0.43 |
| ▸ | BCHE | P06276 | 2/20 | 0.40 |
| ▸ | ACHE | P22303 | 2/20 | 0.40 |
| ▸ | BACE1 | P56817 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.39 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.39 |
| ▸ | HRH2 | P25021 | 1/20 | 0.39 |
| ▸ | HTR2A | P28223 | 1/20 | 0.39 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.39 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | HTR2B | P41595 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 2/20 | 0.39 |
| ▸ | KDM1A | O60341 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205184 | 0.79 | SIGMAR1 (0.44) | ALDH1A1MEN1KMT2ASMN1; SMN2 | |
| SCHEMBL5996543 | 0.75 | TACR1 (0.42) | TACR1KDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL5998249 | 0.71 | — | — | |
| SCHEMBL1889066 | 0.70 | KDM4E (0.67) | KDM4EALDH1A1POLBSLC6A4OPRK1 | |
| Hydrochloric Acid SCHEMBL4811662 | 0.69 | KDM4E (0.65) | KDM4EALDH1A1POLBSLC6A4OPRK1 | |
| Hydrochloric Acid SCHEMBL9620879 | 0.69 | KDM4E (0.65) | KDM4EALDH1A1POLBSLC6A4OPRK1 | |
| SCHEMBL7433455 | 0.69 | KMT2A (0.59) | KDM4EALDH1A1POLBLMNAMEN1 | |
| SCHEMBL7297538 | 0.68 | SLC6A4 (0.49) | TACR1KDM4EALDH1A1HTR2ASLC6A4 | |
| Hydrochloric Acid SCHEMBL9780460 | 0.67 | APOBEC3A (0.50) | TACR1KDM4EALDH1A1HTR2ASLC6A4 | |
| SCHEMBL10567221 | 0.66 | SIGMAR1 (0.53) | KDM4EALDH1A1HTR2ASLC6A4OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0973780-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO -3-(METHYLHYDRAZONO) METHYL-CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT M.B.H. (AT) | 2000-01-26 | — | — | EP | disclosed |
| WO-1998043981-A1 | ANTIBACTERIAL SUBSTITUTED 7-ACYLAMINO-3-(METHYLHYDRAZONO)METHYL -CEPHALOSPORINS AND INTERMEDIATES | BIOCHEMIE GESELLSCHAFT MBH (AT) | 1998-10-08 | — | — | WO | disclosed |