Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 2/20 | 0.58 |
| ▸ | HINT1 | P49773 | 6/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | TAS1R3 | Q7RTX0 | 2/20 | 0.53 |
| ▸ | TAS1R1 | Q7RTX1 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | NT5E | P21589 | 1/20 | 0.51 |
| ▸ | GSK3A | P49840 | 2/20 | 0.51 |
| ▸ | RPS6KA3 | P51812 | 2/20 | 0.51 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.51 |
| ▸ | PNP | P00491 | 1/20 | 0.49 |
| ▸ | TGM2 | P21980 | 1/20 | 0.48 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3812199 | 1.00 | HPGD (0.58) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL13597930 | 1.00 | HPGD (0.58) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL5011969 | 0.92 | HINT1 (0.59) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL14559269 | 0.92 | HINT1 (0.58) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL11910704 | 0.92 | HINT1 (0.58) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL18179095 | 0.92 | HINT1 (0.58) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL2582792 | 0.92 | HPGD (0.56) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL25407962 | 0.90 | ALDH1A1 (0.68) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL14144174 | 0.90 | ALDH1A1 (0.68) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 | |
| SCHEMBL1061031 | 0.90 | ALDH1A1 (0.68) | HPGDHINT1ALDH1A1TAS1R3TAS1R1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20090324708-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF AND A METHOD FOR THE TREATMENT OF RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | UNIVERSIDAD NACIONAL DE QUILMES (AR) | 2009-12-31 | — | — | US | disclosed |
| WO-2008055875-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISION THEREOF AND A METHOD FOR THE TREATMENT OF A RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | UNIVERSIDAD NACIONAL DE QUILMES (AR) | 2008-05-15 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090324708-A1 | COMPOUND HAVING INHIBITORY ACTIVITY ON A RHO-GTPASE CELL PROTEIN, A PROCESS FOR OBTAINING THE SAME, PHARMACEUTICAL COMPOSITIONS COMPRISING THEREOF AND A METHOD FOR THE TREATMENT OF RHO-GTPASE CELL PROTEIN-MEDIATED CONDITION | RHOA, ARHGDIA, ARHGDIB | HPGD 2674/4885HINT1 2800/4885ALDH1A1 4493/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.