Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.68 |
| ▸ | GAA | P10253 | 1/20 | 0.68 |
| ▸ | SDCBP | O00560 | 4/20 | 0.67 |
| ▸ | SDC2 | P34741 | 4/20 | 0.67 |
| ▸ | POLB | P06746 | 2/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 2/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | LTA4H | P09960 | 2/20 | 0.54 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.54 |
| ▸ | MME | P08473 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211172 | 0.89 | ALDH1A1 (0.60) | ALDH1A1GAASDCBPSDC2POLB | |
| SCHEMBL7274235 | 0.83 | ALDH1A1 (0.66) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL11619526 | 0.82 | ALDH1A1 (0.72) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL3454947 | 0.82 | ALDH1A1 (0.56) | ALDH1A1GAASDCBPSDC2POLB | |
| SCHEMBL4861809 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL392680 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL478614 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL30216480 | 0.81 | ALDH1A1 (1.00) | ALDH1A1GAAPOLBL3MBTL1MEN1 | |
| SCHEMBL7063991 | 0.81 | SDCBP (0.49) | ALDH1A1GAASDCBPSDC2POLB | |
| SCHEMBL7063999 | 0.81 | SDCBP (0.49) | ALDH1A1GAASDCBPSDC2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0830371-B1 | IMIDAZO(1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL NV (NL) | 2000-12-20 | — | — | EP | disclosed |
| US-5916888-A | Imidazo 1,5A!pyridine derived serine protease inhibitors | AKZO NOBEL, N.V. (NL) | 1999-06-29 | — | — | US | disclosed |
| EP-0830371-A1 | IMIDAZO 1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | Akzo Nobel N.V. (NL) | 1998-03-25 | — | — | EP | disclosed |
| WO-1996038470-A1 | IMIDAZO[1,5a]PYRIDINE DERIVED SERINE PROTEASE INHIBITORS | AKZO NOBEL N.V. (NL) | 1996-12-05 | — | — | WO | disclosed |