Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.59 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.59 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.59 |
| ▸ | LMNA | P02545 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | CASP3 | P42574 | 1/20 | 0.44 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.44 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14667474 | 1.00 | MAPT (0.59) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL22268377 | 0.83 | ALDH1A1 (0.50) | MAPTPKMCDK5CDK5R1MAPK1 | |
| SCHEMBL212911 | 0.82 | MAPT (0.60) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL11963959 | 0.82 | MAPT (0.60) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL14667470 | 0.82 | MAPT (0.60) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL2374640 | 0.82 | CES2 (0.47) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL2374643 | 0.82 | CES2 (0.47) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL14193661 | 0.81 | LMNA (0.56) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL92080 | 0.81 | MAPT (0.78) | MAPTPKMCDK5CDK5R1LMNA | |
| SCHEMBL1357956 | 0.81 | MAPT (0.78) | MAPTPKMCDK5CDK5R1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6139991-A | NONAQUEOUS SOLVENT, ELECTROLYTE AND CARBONIC ESTER | UBE INDUSTRIES, LTD. (JP) | 2000-10-31 | — | — | US | disclosed |
| US-3933846-A | FUNGICIDES, OVICIDES | BAYER AKTIENGESELLSCHAFT (DT) | 1976-01-20 | — | — | US | disclosed |