Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | PTBP1 | P26599 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | FBP1 | P09467 | 4/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3047715 | 0.86 | CA2 (0.50) | LMNAMEN1KMT2ATDP1SMN1; SMN2 | |
| SCHEMBL25738956 | 0.81 | ALDH1A1 (0.56) | LMNAPTBP1MEN1KMT2AMAPT | |
| SCHEMBL25738537 | 0.78 | MEN1 (0.56) | LMNAPTBP1MEN1KMT2AMAPT | |
| SCHEMBL5475723 | 0.75 | KMT2A (0.64) | LMNAMEN1KMT2APOLBTDP1 | |
| SCHEMBL9024308 | 0.74 | LMNA (0.60) | LMNAPTBP1MEN1KMT2AMAPT | |
| SCHEMBL12060827 | 0.74 | LMNA (0.63) | LMNAPTBP1MEN1KMT2AMAPT | |
| SCHEMBL18292573 | 0.71 | ALDH1A1 (0.61) | LMNAMAPTPOLBTDP1SMN1; SMN2 | |
| SCHEMBL31267580 | 0.71 | NPC1 (0.60) | LMNAPOLBSMN1; SMN2ALDH1A1NPC1 | |
| SCHEMBL3843062 | 0.71 | SMN1; SMN2 (0.74) | MEN1KMT2AMAPTPOLBSMN1; SMN2 | |
| SCHEMBL9828792 | 0.70 | LMNA (0.67) | LMNAMEN1KMT2APOLBSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008033389-A2 | MACROCYCLIC HCV INHIBITORS AND THEIR USES | NOVARTIS AG (CH) | 2008-03-20 | — | — | WO | disclosed |