Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.47 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 2/20 | 0.41 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.40 |
| ▸ | BLK | P51451 | 1/20 | 0.40 |
| ▸ | BTK | Q06187 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206685 | 0.83 | CASP3 (0.52) | CASP3NPC1RAB9AMAOASMN1; SMN2 | |
| SCHEMBL8205935 | 0.74 | SIRT2 (0.50) | NPC1RAB9AMAOAMCL1SIRT2 | |
| SCHEMBL8197914 | 0.73 | TACR3 (0.55) | CASP3NPC1RAB9ATP53MAPT | |
| SCHEMBL8207158 | 0.73 | NPC1 (0.54) | CASP3NPC1RAB9AL3MBTL1 | |
| SCHEMBL6191271 | 0.71 | NPC1 (0.45) | CASP3NPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL16088310 | 0.71 | NPC1 (0.61) | CASP3NPC1RAB9AMAOASMN1; SMN2 | |
| SCHEMBL28564954 | 0.71 | NPC1 (0.64) | CASP3NPC1RAB9AMAOASMN1; SMN2 | |
| SCHEMBL4201818 | 0.68 | NPC1 (0.57) | CASP3NPC1RAB9AMAOASMN1; SMN2 | |
| SCHEMBL7659684 | 0.68 | CASP3 (0.46) | CASP3NPC1RAB9ASMN1; SMN2RECQL | |
| SCHEMBL6929631 | 0.68 | NPC1 (0.63) | CASP3NPC1RAB9AMAOASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0979227-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | Takeda Chemical Industries, Ltd. (JP) | 2000-02-16 | — | — | EP | disclosed |
| WO-1998047882-A1 | 4,1-BENZOXAZEPINES, THEIR ANALOGUES, AND THEIR USE AS SOMATOSTATIN AGONISTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1998-10-29 | — | — | WO | disclosed |