SCHEMBL8205941

SCHEMBL8205941

O=C(Oc1c(Cl)cc(Cl)cc1Cl)c1ccccc1O

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 4/20 0.54
HSD17B10 Q99714 3/20 0.54
ALOX15 P16050 1/20 0.54
ALDH1A1 P00352 7/20 0.50
KDM4E B2RXH2 5/20 0.50
LMNA P02545 1/20 0.49
TSHR P16473 1/20 0.49
ESR1 P03372 3/20 0.47
ESR2 Q92731 3/20 0.47
TDP1 Q9NUW8 3/20 0.46
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 2/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
FADS1 O60427 1/20 0.42
KCNMA1 Q12791 1/20 0.42
PKM P14618 1/20 0.41
TP53 P04637 1/20 0.41
CA12 O43570 1/20 0.41
CA1 P00915 1/20 0.41

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9169328 0.90 KMT2A (0.42) HPGDALDH1A1ESR1ESR2MEN1
SCHEMBL8209348 0.86 HPGD (0.58) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL9702711 0.83 ALDH1A1 (0.49) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL28911408 0.81 HPGD (0.66) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL12919768 0.81 HPGD (0.59) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL8210159 0.81 ESR1 (0.58) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL8209293 0.77 MAPT (0.47) HPGDLMNATSHRESR1ESR2
SCHEMBL6659667 0.76 HPGD (0.73) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL31557557 0.76 HPGD (0.73) HPGDHSD17B10ALOX15ALDH1A1KDM4E
SCHEMBL8204774 0.76 HPGD (0.67) HPGDHSD17B10ALOX15ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed