Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.43 |
| ▸ | STAT3 | P40763 | 1/20 | 0.41 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8205946 | 0.84 | ACE (0.50) | OPRM1SLC6A2 | |
| SCHEMBL7641458 | 0.80 | XIAP (0.44) | OPRM1OPRD1 | |
| SCHEMBL5062693 | 0.78 | TACR1 (0.43) | OPRM1SLC6A2 | |
| SCHEMBL366333 | 0.76 | TACR1 (0.51) | — | |
| SCHEMBL6885771 | 0.76 | TACR1 (0.44) | OPRM1 | |
| SCHEMBL7624015 | 0.73 | CMA1 (0.42) | — | |
| SCHEMBL615204 | 0.72 | TDP1 (0.41) | OPRM1OPRD1 | |
| SCHEMBL5063463 | 0.72 | OPRM1 (0.45) | OPRM1 | |
| SCHEMBL1800549 | 0.72 | ACE (0.42) | — | |
| SCHEMBL2029990 | 0.71 | TACR1 (0.52) | OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5480779-A | ADDING TO SAMPLE PREDETERMINED AMOUNT OF ISOMERASE ISOMERIZING PEPTIDE N-TERMINAL TO PROLINE, MEASURING ENZYME-CATALYZED ISOMERIZATION OF PROLINE-CONTAINING PEPTIDE SUBSTRATE, DETERMINING CYCLOSPORIN CONCENTRATION FROM CALIBRATION CURVE | ARZNEIMITTELWERK DRESDEN GMBH (DE) | 1996-01-02 | — | — | US | disclosed |