SCHEMBL8206089

SCHEMBL8206089

O=C(Oc1c(Br)cccc1Br)c1ccccc1O

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.58
HSD17B10 Q99714 4/20 0.58
ALOX15 P16050 1/20 0.58
KDM4E B2RXH2 6/20 0.53
ALDH1A1 P00352 5/20 0.53
LMNA P02545 2/20 0.52
TSHR P16473 2/20 0.52
MAOB P27338 2/20 0.49
TDP1 Q9NUW8 2/20 0.47
KMT2A Q03164 4/20 0.45
GAA P10253 2/20 0.45
POLB P06746 2/20 0.45
SMN1; SMN2 Q16637 2/20 0.44
MPO P05164 1/20 0.44
HIF1A Q16665 1/20 0.44
CA12 O43570 1/20 0.44
CA1 P00915 1/20 0.44
CA2 P00918 1/20 0.44
HMGB1 P09429 1/20 0.44
CA4 P22748 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29865672 0.86 HPGD (0.54) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL8209230 0.86 HPGD (0.54) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL8205209 0.82 HPGD (0.67) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL9304475 0.79 HSD17B10 (0.58) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL8209348 0.79 HPGD (0.58) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL12919768 0.76 HPGD (0.59) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL18263212 0.76 LMNA (0.50) HSD17B10ALOX15ALDH1A1LMNATSHR
SCHEMBL8205558 0.75 HPGD (0.73) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL7614991 0.75 HPGD (0.88) HPGDHSD17B10ALOX15KDM4EALDH1A1
SCHEMBL28634833 0.75 HPGD (0.57) HPGDHSD17B10ALOX15KDM4EALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US claimed
US-6117562-A A THERMAL IMAGE TRANSFER INK LAYER FORMED ON THE SUPPORT; INK LAYER COMPRISING A COLORING AGENT, A RESIN AND A PLASTICIZER FOR LOWERING THE MELT VISCOSITY OF RESIN RICOH COMPANY, LTD. (JP) 2000-09-12 US disclosed
US-5716477-A CONSISTS OF A SUPPORT AND THERMAL IMAGE TRANSFER INK LAYER FORMED ON SAID SUPPORT CONSISTS OF A COLORING AGENT AND A PLASTICIZER FOR LOWERING MELT VISCOSITY OF THE RESIN, HIGH THERMOSENSITIVITY ON CLOTH, PLASTIC, OR PAPER RECEIVER RICOH COMPANY, LTD. (JP) 1998-02-10 US disclosed
US-4562448-A Heat-sensitive transfer medium RICOH CO., LTD. (JP) 1985-12-31 US disclosed
US-4513052-A LEUCO DYE, FLUORAN DYE AND A PHENOLIC COMPOUND RICOH CO., LTD. (JP) 1985-04-23 US disclosed