SCHEMBL28634833

SCHEMBL28634833

O=C(Oc1ccc(Br)c(Br)c1Br)c1ccccc1O

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 6/20 0.57
KDM4E B2RXH2 5/20 0.57
ALDH1A1 P00352 5/20 0.57
HSD17B10 Q99714 4/20 0.57
ALOX15 P16050 1/20 0.53
TSHR P16473 2/20 0.47
LMNA P02545 1/20 0.47
KMT2A Q03164 4/20 0.45
GAA P10253 2/20 0.45
POLB P06746 1/20 0.45
TDP1 Q9NUW8 2/20 0.44
ESR1 P03372 3/20 0.42
ESR2 Q92731 3/20 0.42
MEN1 O00255 1/20 0.42
MAPT P10636 2/20 0.41
USP2 O75604 1/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
MPO P05164 1/20 0.41
HIF1A Q16665 1/20 0.41
CA12 O43570 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8205209 0.81 HPGD (0.67) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL8205417 0.79 HPGD (0.59) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL11657206 0.79 ALDH1A1 (0.38) HPGDKDM4EALDH1A1HSD17B10LMNA
SCHEMBL3635482 0.77 HPGD (0.76) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL7038760 0.76 HSD17B10 (0.74) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL8206089 0.75 HPGD (0.58) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL10934336 0.74 TDP1 (0.34) ALDH1A1LMNAKMT2ATDP1MAPT
SCHEMBL10686808 0.74 HSD17B10 (0.71) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL4447222 0.73 HPGD (0.60) HPGDKDM4EALDH1A1HSD17B10ALOX15
SCHEMBL8854452 0.73 ESR1 (0.68) HPGDKDM4EALDH1A1HSD17B10ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-113480835-A Glass film and preparation method thereof 张钊 2021-10-08 CN claimed
CN-113480835-A Glass film and preparation method thereof 张钊 2021-10-08 CN disclosed