Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | CA2 | P00918 | 2/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | ADRA2A | P08913 | 2/20 | 0.38 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.36 |
| ▸ | HDAC4 | P56524 | 2/20 | 0.36 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.36 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206064 | 0.80 | ALKBH3 (0.36) | CA1CA2CA12CA7CA9 | |
| SCHEMBL8201027 | 0.78 | DYRK1A (0.39) | CYP2D6HDAC4HDAC8MAPTKDM4E | |
| SCHEMBL8204972 | 0.77 | ALDH1A1 (0.34) | CYP2D6ALDH1A1MAPTKDM4E | |
| SCHEMBL8201016 | 0.74 | CYP19A1 (0.35) | CA9KCNH2ALDH1A1HPGDMAPT | |
| SCHEMBL196223 | 0.69 | CA12 (0.68) | CYP2D6CA1CA2CA12CA7 | |
| SCHEMBL28280300 | 0.67 | HDAC4 (0.55) | CYP2D6CA1CA2CA12CA7 | |
| SCHEMBL487152 | 0.66 | CYP2D6 (0.67) | CYP2D6CA1CA2CA12CA7 | |
| SCHEMBL29897446 | 0.66 | CYP2D6 (0.49) | CYP2D6CA1CA2CA12CA7 | |
| SCHEMBL7112710 | 0.66 | CYP2D6 (0.49) | CYP2D6CA1CA2CA12CA7 | |
| SCHEMBL15635353 | 0.66 | CYP2D6 (0.49) | CYP2D6CA1CA2CA12CA7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |