Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | TGFBR1 | P36897 | 3/20 | 0.34 |
| ▸ | ACVR1 | Q04771 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ACVR1B | P36896 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | FYN | P06241 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | CA9 | Q16790 | 1/20 | 0.33 |
| ▸ | SLC10A2 | Q12908 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8204972 | 0.82 | ALDH1A1 (0.34) | KDM4EALDH1A1GAACYP3A4MAPT | |
| SCHEMBL8206064 | 0.76 | ALKBH3 (0.36) | MAPTCA9 | |
| SCHEMBL8206097 | 0.74 | CYP2D6 (0.43) | KDM4EALDH1A1HPGDKCNH2ACHE | |
| SCHEMBL8201027 | 0.74 | DYRK1A (0.39) | KDM4ECYP3A4MAPT | |
| SCHEMBL721861 | 0.64 | ACHE (0.65) | KDM4EALDH1A1HPGDL3MBTL1ACHE | |
| SCHEMBL21275892 | 0.63 | ACHE (0.41) | ACHEGAACYP3A4MAPTCA9 | |
| SCHEMBL15219673 | 0.62 | GABRA1 (0.47) | KDM4EALDH1A1ACHEGAACYP3A4 | |
| SCHEMBL683553 | 0.61 | ACHE (0.54) | L3MBTL1ACHECYP3A4MAPTCA9 | |
| SCHEMBL1541914 | 0.61 | ACHE (0.59) | KDM4EALDH1A1HPGDL3MBTL1ACHE | |
| SCHEMBL9730287 | 0.60 | ACHE (0.52) | L3MBTL1ACHECYP3A4MAPTCA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |