Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | CYP1A1 | P04798 | 4/20 | 0.33 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.33 |
| ▸ | ABL1 | P00519 | 4/20 | 0.33 |
| ▸ | ABCB1 | P08183 | 4/20 | 0.33 |
| ▸ | BCR | P11274 | 4/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.33 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.33 |
| ▸ | CYP2C8 | P10632 | 2/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.33 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.33 |
| ▸ | CYP4B1 | P13584 | 2/20 | 0.33 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.33 |
| ▸ | CYP3A5 | P20815 | 2/20 | 0.33 |
| ▸ | CYP2A7 | P20853 | 2/20 | 0.33 |
| ▸ | CYP3A7 | P24462 | 2/20 | 0.33 |
| ▸ | CYP2F1 | P24903 | 2/20 | 0.33 |
| ▸ | CYP2C18 | P33260 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8201027 | 0.85 | DYRK1A (0.39) | CYP1A1CYP1B1CYP1A2CYP2E1CYP3A4 | |
| SCHEMBL8206064 | 0.84 | ALKBH3 (0.36) | ABL1ABCB1BCRPTGS2MAPT | |
| SCHEMBL8201016 | 0.82 | CYP19A1 (0.35) | ALDH1A1CYP3A4GAAMAPTKDM4E | |
| SCHEMBL8206097 | 0.77 | CYP2D6 (0.43) | ALDH1A1CYP2D6MAPTKDM4E | |
| SCHEMBL8200077 | 0.71 | PTGS2 (0.35) | TRPV1PTGS2 | |
| SCHEMBL8200061 | 0.61 | ALDH1A1 (0.33) | ALDH1A1CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL2954516 | 0.61 | ALDH1A1 (0.79) | ALDH1A1CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL17514635 | 0.61 | ALDH1A1 (0.58) | ALDH1A1CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL27574576 | 0.60 | CYP2D6 (0.50) | ALDH1A1CYP1A1CYP1B1ABL1ABCB1 | |
| SCHEMBL17522141 | 0.60 | FKBP1A (0.45) | ALDH1A1CYP3A4TRPV1GAANPBWR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6140344-A | FOR TREATING PATHOLOGICAL CONDITIONS SUCH AS ASTHMA, RHINITIS, ECZEMA AND PARASITIC INFECTIONS FEATURING TISSUE EOSINOPHILIA | SYNTEX (U.S.A.) INC. (US) | 2000-10-31 | — | — | US | disclosed |