Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | EPHX1 | P07099 | 3/20 | 0.45 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | SIRT1 | Q96EB6 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | PARP1 | P09874 | 1/20 | 0.41 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | BLM | P54132 | 1/20 | 0.41 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6686346 | 0.82 | EPHX1 (0.45) | CYP2C19HSD17B10EPHX1LMNASIRT1 | |
| SCHEMBL5902536 | 0.78 | EPHX1 (0.42) | CYP2C19HSD17B10EPHX1LMNASIRT1 | |
| SCHEMBL2311192 | 0.78 | EPHX1 (0.66) | HSD17B10EPHX1LMNAL3MBTL1TDP1 | |
| SCHEMBL6796251 | 0.77 | EPHX1 (0.71) | EPHX1LMNAPOLBL3MBTL1MAPT | |
| SCHEMBL11495800 | 0.76 | CYP2C9 (0.44) | CYP2C19HSD17B10CYP2C9LMNAPOLB | |
| SCHEMBL3959622 | 0.74 | HTT (0.53) | EPHX1LMNAPOLBL3MBTL1SMN1; SMN2 | |
| SCHEMBL4595950 | 0.74 | EPHX1 (0.43) | CYP2C19HSD17B10EPHX1LMNASIRT1 | |
| SCHEMBL15768221 | 0.73 | LMNA (0.43) | CYP2C19HSD17B10CYP2C9EPHX1LMNA | |
| SCHEMBL15781198 | 0.73 | LMNA (0.43) | CYP2C19HSD17B10CYP2C9EPHX1LMNA | |
| SCHEMBL11021419 | 0.72 | MAOA (0.47) | CYP2C19EPHX1CYP3A4FFAR1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2004744-B1 | COMPOSITION INCLUDING MULTIPLE FUNCTIONALIZED POLYMERS | BRIDGESTONE CORP (JP) | 2017-12-06 | — | — | EP | disclosed |
| EP-2277948-B1 | Polyhedral-modified polymer | BRIDGESTONE CORP (JP) | 2015-02-18 | — | — | EP | disclosed |
| EP-1805223-B1 | FUNCTIONALIZED POLYMER WITH LINKING GROUP | BRIDGESTONE CORP (JP) | 2014-12-24 | — | — | EP | disclosed |
| US-8623955-B2 | Polyhedral-modified polymer | BRIDGESTONE CORPORATION (JP) | 2014-01-07 | — | — | US | disclosed |
| EP-1885775-B1 | ENHANCING INTERACTIVITY BETWEEN AMINE-FUNCTIONALIZED POLYMERS AND PARTICULATE FILLERS | BRIDGESTONE CORP (JP) | 2013-07-24 | — | — | EP | disclosed |
| US-20130041096-A1 | POLYHEDRAL-MODIFIED POLYMER | BRIDGESTONE CORPORATION (JP) | 2013-02-14 | — | — | US | disclosed |
| US-8236888-B2 | Polyhedral-modified polymer | BRIDGESTONE CORPORATION (JP) | 2012-08-07 | — | — | US | disclosed |
| US-20120010355-A1 | POLYHEDRAL-MODIFIED POLYMER | BRIDGESTONE CORPORATION (JP) | 2012-01-12 | — | — | US | disclosed |
| US-8063153-B2 | Functionalized polymer with linking group | BRIDGESTONE CORPORATION (JP) | 2011-11-22 | — | — | US | disclosed |
| US-7999029-B2 | Polyhedral-modified polymer | BRIDGESTONE CORPORATION (JP) | 2011-08-16 | — | — | US | disclosed |
| US-20070149744-A1 | Functionalized polymer with linking group | BRIDGESTONE CORPORATION (JP) | 2007-06-28 | — | — | US | disclosed |
| US-20070037956-A1 | enhanced interactivity with carbon black filler; tire treads; nitroso nitrogen atom reacts at living polymer anion end to give hydroxyamine or oxyamine group bonded to the elastomer chain; quenched with alcohol or acid at N-O oxygen; butadiene-styrene copolymer functionalized with nitrosobenzene | BRIDGESTONE CORP. (JP) | 2007-02-15 | — | — | US | disclosed |
| WO-2006128158-A1 | ENHANCING INTERACTIVITY BETWEEN AMINE-FUNCTIONALIZED POLYMERS AND PARTICULATE FILLERS | BRIDGESTONE CORPORATION (JP) | 2006-11-30 | — | — | WO | disclosed |
| WO-2006050486-A1 | POLYHEDRAL-MODIFIED POLYMER | BRIDGESTONE CORPORATION (JP) | 2006-05-11 | — | — | WO | disclosed |
| WO-2006047328-A1 | FUNCTIONALIZED POLYMER WITH LINKING GROUP | BRIDGESTONE CORPORATION (JP) | 2006-05-04 | — | — | WO | disclosed |
| EP-0519188-B1 | Process for producing vulcanised carbon black-filled plastics and rubber compositions | DEGUSSA (DE) | 1997-03-26 | — | — | EP | disclosed |
| US-5401789-A | Reacting an organosilicon compound with the carbon black | DEGUSSA AKTIENGESELLSCHAFT (DE) | 1995-03-28 | — | — | US | disclosed |
| EP-0519188-A1 | Process for producing vulcanised carbon black-filled plastics and rubber compositions | Degussa Aktiengesellschaft (DE) | 1992-12-23 | — | — | EP | disclosed |
| US-5159009-A | CARBON BLACKS MODIFIED WITH ORGANOSILICON COMPOUNDS, METHOD OF THEIR PRODUCTION AND THEIR USE IN RUBBER MIXTURES | DEGUSSA (DE) | 1992-10-27 | — | — | US | disclosed |
| EP-0468140-A2 | With organosilicium-compound chemically modified carbon blacks, method for their preparation and their use | Degussa Aktiengesellschaft (DE) | 1992-01-29 | — | — | EP | disclosed |