Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CHRM2 | P08172 | 3/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.40 |
| ▸ | KDM1A | O60341 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.36 |
| ▸ | MAOB | P27338 | 1/20 | 0.36 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 4/20 | 0.33 |
| ▸ | SCN5A | Q14524 | 2/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.33 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.33 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197966 | 0.97 | CHRM3 (0.40) | CHRM2CHRM1CHRM3OPRM1MEN1 | |
| SCHEMBL8206408 | 0.94 | CHRM2 (0.42) | CHRM2CHRM1CHRM3OPRM1MEN1 | |
| SCHEMBL8208907 | 0.85 | CHRM2 (0.40) | CHRM2CHRM1CHRM3ACKR3GRIN2B | |
| SCHEMBL8209774 | 0.84 | CHRM3 (0.40) | CHRM2CHRM1CHRM3OPRM1MEN1 | |
| SCHEMBL8209778 | 0.84 | CHRM3 (0.40) | CHRM2CHRM1CHRM3OPRM1MEN1 | |
| SCHEMBL8197961 | 0.83 | OPRM1 (0.38) | CHRM2CHRM1CHRM3OPRM1MEN1 | |
| SCHEMBL8199243 | 0.82 | GRIN2B (0.46) | OPRM1GRIN2BGRIN1 | |
| SCHEMBL8209728 | 0.82 | HRH1 (0.42) | CHRM2CHRM3OPRM1GRIN2BKCNH2 | |
| SCHEMBL8211310 | 0.80 | OPRM1 (0.39) | CHRM2CHRM1CHRM3OPRM1GRIN2B | |
| SCHEMBL8206446 | 0.80 | OPRM1 (0.38) | CHRM2CHRM1CHRM3OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |