Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.37 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.37 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.37 |
| ▸ | UBE2M | P61081 | 1/20 | 0.35 |
| ▸ | DCUN1D1 | Q96GG9 | 1/20 | 0.35 |
| ▸ | ACKR3 | P25106 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 2/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.34 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.34 |
| ▸ | KCNE1 | P15382 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197961 | 0.95 | OPRM1 (0.38) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| SCHEMBL8206406 | 0.90 | UBE2M (0.40) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| SCHEMBL8208910 | 0.86 | HSD11B1 (0.46) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| SCHEMBL8199247 | 0.83 | AGTR2 (0.42) | OPRM1CHRM3CHRM2CHRM1HTR2A | |
| SCHEMBL8209781 | 0.83 | OPRM1 (0.37) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| SCHEMBL8209731 | 0.82 | HRH1 (0.39) | OPRM1CHRM3CHRM2CHRM1HTR2A | |
| SCHEMBL8206408 | 0.81 | CHRM2 (0.42) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| SCHEMBL8199191 | 0.80 | CHRM2 (0.38) | OPRM1CHRM3CHRM2CHRM1HTR2A | |
| SCHEMBL8206448 | 0.80 | CHRM2 (0.41) | OPRM1MEN1OPRD1KMT2ACHRM3 | |
| Hydrochloric Acid SCHEMBL8209836 | 0.79 | AGTR2 (0.47) | OPRM1OPRD1OPRK1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |