Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 3/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 1/20 | 0.56 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.49 |
| ▸ | RECQL | P46063 | 1/20 | 0.49 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7893018 | 0.92 | NR1H4 (0.56) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8207730 | 0.92 | ALDH1A1 (0.51) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8200517 | 0.88 | SMN1; SMN2 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8199066 | 0.87 | LMNA (0.52) | SMN1; SMN2MEN1KMT2AMAPTHPGD | |
| SCHEMBL8207045 | 0.86 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8206984 | 0.86 | ALDH1A1 (0.54) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8200394 | 0.84 | HPGD (0.55) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL7428203 | 0.84 | ALDH1A1 (0.53) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8207378 | 0.81 | ALDH1A1 (0.48) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT | |
| SCHEMBL8245383 | 0.80 | ROCK2 (0.52) | ALDH1A1SMN1; SMN2MEN1KMT2AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |