Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.35 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.35 |
| ▸ | PLAAT3 | P53816 | 2/20 | 0.35 |
| ▸ | PLAAT5 | Q96KN8 | 2/20 | 0.35 |
| ▸ | PLAAT2 | Q9NWW9 | 2/20 | 0.35 |
| ▸ | PLAAT4 | Q9UL19 | 2/20 | 0.35 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.34 |
| ▸ | HTR3B | O95264 | 1/20 | 0.34 |
| ▸ | HTR3A | P46098 | 1/20 | 0.34 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.34 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GFER | P55789 | 2/20 | 0.34 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.34 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.33 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8199243 | 0.86 | GRIN2B (0.46) | SIGMAR1OPRM1 | |
| SCHEMBL8199090 | 0.85 | GRIN2B (0.43) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL8199533 | 0.83 | GRIN2B (0.43) | POLBPLAAT3PLAAT5PLAAT2PLAAT4 | |
| SCHEMBL8199188 | 0.82 | GRIN2B (0.40) | SIGMAR1ADRB2CHRM2CHRM4ADRB1 | |
| Hydrochloric Acid SCHEMBL8209834 | 0.82 | GRIN2B (0.46) | SIGMAR1OPRM1 | |
| SCHEMBL8209728 | 0.81 | HRH1 (0.42) | PLAAT3PLAAT5PLAAT2PLAAT4ALDH1A1 | |
| SCHEMBL8199053 | 0.81 | TAAR1 (0.50) | ALDH1A1ADRB2CHRM2CHRM4ADRB1 | |
| SCHEMBL8205354 | 0.80 | MEN1 (0.43) | ALDH1A1SIGMAR1OPRM1LMNAMEN1 | |
| SCHEMBL8208907 | 0.80 | CHRM2 (0.40) | ALDH1A1HSD11B1CHRM2CHRM4CHRM5 | |
| SCHEMBL8205244 | 0.80 | TAAR1 (0.49) | ALDH1A1SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |