Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | GPR17 | Q13304 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
| ▸ | MCL1 | Q07820 | 8/20 | 0.33 |
| ▸ | BCL2 | P10415 | 3/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8202821 | 0.76 | LMNA (0.44) | HCAR2CYP1A2CYP2C9LMNAALDH1A1 | |
| SCHEMBL5612429 | 0.74 | HCAR2 (0.40) | HCAR2LMNAALDH1A1KDM4EHSD17B10 | |
| SCHEMBL9816497 | 0.70 | MCL1 (0.67) | ALDH1A1KDM4EHSD17B10MCL1BCL2 | |
| SCHEMBL8203697 | 0.67 | HPGD (0.59) | LMNAALDH1A1KDM4EHPGD | |
| SCHEMBL28610448 | 0.67 | HCAR2 (0.39) | HCAR2CYP2C9LMNAALDH1A1KDM4E | |
| SCHEMBL9955516 | 0.66 | ALDH1A1 (0.46) | HCAR2LMNAALDH1A1HPGDHSD17B10 | |
| SCHEMBL1126546 | 0.65 | HPGD (0.64) | CYP1A2CYP2C9LMNAALDH1A1KDM4E | |
| SCHEMBL17797893 | 0.64 | TSHR (0.46) | HCAR2CYP1A2LMNAALDH1A1KDM4E | |
| SCHEMBL5611550 | 0.64 | TSHR (0.34) | HCAR2ALDH1A1 | |
| SCHEMBL17797824 | 0.63 | TSHR (0.38) | HCAR2CYP1A2CYP2C9ALDH1A1MCL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0591355-B1 | PORPHYCENE COMPOUNDS FOR PHOTODYNAMIC THERAPY | CYTOPHARM INC (US) | 2000-03-08 | — | — | EP | disclosed |
| US-5409900-A | Treatment of cancer tumors, psoriasis; purification of blood | CYTOPHARM, INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5262401-A | Porphyrins as antitumor agents and psoriasis treatment | CYTOPHARM, INC. (US) | 1993-11-16 | — | — | US | disclosed |
| US-5179120-A | Antitumor agents or psoriasis | CYTOPHARM, INC. (US) | 1993-01-12 | — | — | US | disclosed |