SCHEMBL8207207

SCHEMBL8207207

CCCC(=O)Oc1ccccc1I

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.51
KMT2A Q03164 2/20 0.51
KDM4E B2RXH2 1/20 0.51
RECQL P46063 1/20 0.51
ALOX15 P16050 1/20 0.46
LMNA P02545 1/20 0.46
FABP7 O15540 1/20 0.42
FABP3 P05413 1/20 0.42
FABP5 Q01469 1/20 0.42
BCL9 O00512 1/20 0.41
CTNNB1 P35222 1/20 0.41
POLM Q9NP87 1/20 0.40
POLK Q9UBT6 1/20 0.40
POLL Q9UGP5 1/20 0.40
POLH Q9Y253 1/20 0.40
ALDH1A1 P00352 2/20 0.39
PKM P14618 1/20 0.38
PTGS2 P35354 1/20 0.38
PDGFRB P09619 1/20 0.38
PDGFRA P16234 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL370102 0.90 KMT2A (0.65) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL27546336 0.87 KMT2A (0.57) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL30942571 0.87 KMT2A (0.57) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL9312497 0.87 KMT2A (0.59) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL4246889 0.85 ELANE (0.46) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL29435434 0.85 ELANE (0.46) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL15548829 0.81 KMT2A (0.54) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL15548744 0.80 PTGS2 (0.54) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL1792324 0.80 L3MBTL1 (0.56) MEN1KMT2AKDM4ERECQLALOX15
SCHEMBL10580118 0.80 KMT2A (0.53) MEN1KMT2AKDM4ERECQLALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101380317-B Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD 2010-12-08 CN claimed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN claimed
EP-3106472-B1 LIVING RADICAL POLYMERIZATION CATALYST, AND POLYMER PRODUCTION METHOD USING SAME UNIV KYOTO (JP) 2024-05-29 EP disclosed
US-9926386-B2 Living radical polymerization catalyst, and polymer production method using same KYOTO UNIVERSITY (JP) 2018-03-27 US disclosed
EP-3106472-A1 LIVING RADICAL POLYMERIZATION CATALYST, AND POLYMER PRODUCTION METHOD USING SAME Kyoto University (JP) 2016-12-21 EP disclosed
US-20160347872-A1 LIVING RADICAL POLYMERIZATION CATALYST, AND POLYMER PRODUCTION METHOD USING SAME KYOTO UNIVERSITY (JP) 2016-12-01 US disclosed
CN-101380317-B Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV PHARMACEUTICAL CO LTD 2010-12-08 CN disclosed
CN-101380317-A Pharmaceutical composition for relieving pruritus CAYMAN ISLAND SHANGANSHENG DEV (CN) 2009-03-11 CN disclosed
US-6124109-A System for qualitatively and/or quantitatively analyzing preferably biological substances using enhanced chemiluminescence, and method and analysis kit using same INNOGENETICS N.V. (BE) 2000-09-26 US disclosed