Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 2/20 | 0.78 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.43 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | TP53 | P04637 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206297 | 0.97 | SLC6A9 (0.79) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL8212306 | 0.92 | SLC6A9 (0.76) | SLC6A9ENPP2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL8207198 | 0.88 | SLC6A9 (1.00) | SLC6A9ENPP2TP53MAPT | |
| SCHEMBL8211327 | 0.88 | SLC6A9 (0.75) | SLC6A9ENPP2SLC6A4SLC6A3SLC6A2 | |
| SCHEMBL9535367 | 0.86 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9537085 | 0.83 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9535785 | 0.83 | SLC6A9 (0.58) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9537927 | 0.82 | LMNA (0.55) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9537811 | 0.82 | SLC6A9 (0.60) | SLC6A9ENPP2TP53MAPTLMNA | |
| SCHEMBL9535970 | 0.81 | SLC6A9 (0.55) | SLC6A9ENPP2TP53MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059922-A2 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999044596-A2 | GLYCINE TRANSPORT INHIBITORS | JANSSEN PHARMACEUTICA N.V. (BE) | 1999-09-10 | — | — | WO | disclosed |