Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | LTA4H | P09960 | 1/20 | 0.35 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | GABRP | O00591 | 2/20 | 0.30 |
| ▸ | GABRD | O14764 | 2/20 | 0.30 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.30 |
| ▸ | GABRB1 | P18505 | 2/20 | 0.30 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.30 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.30 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.30 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.30 |
| ▸ | GABRA2 | P47869 | 2/20 | 0.30 |
| ▸ | GABRB2 | P47870 | 2/20 | 0.30 |
| ▸ | GABRA4 | P48169 | 2/20 | 0.30 |
| ▸ | GABRE | P78334 | 2/20 | 0.30 |
| ▸ | GABRA6 | Q16445 | 2/20 | 0.30 |
| ▸ | GABRG1 | Q8N1C3 | 2/20 | 0.30 |
| ▸ | GABRG3 | Q99928 | 2/20 | 0.30 |
| ▸ | GABRQ | Q9UN88 | 2/20 | 0.30 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206628 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8356433 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8199703 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8206575 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8207026 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8212112 | 0.92 | LTA4H (0.37) | SLC7A5LTA4HDPP4 | |
| SCHEMBL8210432 | 0.84 | FAAH (0.40) | — | |
| SCHEMBL5730954 | 0.79 | LTA4H (0.31) | LTA4H | |
| SCHEMBL13934948 | 0.77 | CES2 (0.44) | SLC7A5DPP4DPP8DPP9DPP7 | |
| SCHEMBL13934353 | 0.77 | CES2 (0.44) | SLC7A5DPP4DPP8DPP9DPP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0971923-A2 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 2000-01-19 | — | — | EP | disclosed |
| US-5869493-A | ANTIVIRALS AGAINST HERPES AND RETROVIRUSES | MEDIVIR AB (SE) | 1999-02-09 | — | — | US | disclosed |
| WO-1998034917-A2 | SYNTHESIS OF ACYCLIC NUCLEOSIDE DERIVATIVES | MEDIVIR AB (SE) | 1998-08-13 | — | — | WO | disclosed |