Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 1/20 | 0.37 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.35 |
| ▸ | CES2 | O00748 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | PTPN7 | P35236 | 3/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | FAAH | O00519 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206575 | 1.00 | LTA4H (0.37) | LTA4HSLC7A5CES2DPP4PTPN7 | |
| SCHEMBL8212112 | 1.00 | LTA4H (0.37) | LTA4HSLC7A5CES2DPP4PTPN7 | |
| SCHEMBL8199703 | 1.00 | LTA4H (0.37) | LTA4HSLC7A5CES2DPP4PTPN7 | |
| SCHEMBL8206628 | 1.00 | LTA4H (0.37) | LTA4HSLC7A5CES2DPP4PTPN7 | |
| SCHEMBL8207026 | 1.00 | LTA4H (0.37) | LTA4HSLC7A5CES2DPP4PTPN7 | |
| SCHEMBL8207451 | 0.92 | SLC7A5 (0.38) | LTA4HSLC7A5DPP4 | |
| SCHEMBL8210432 | 0.91 | FAAH (0.40) | PTPN7MEN1FAAHKMT2A | |
| SCHEMBL4352315 | 0.78 | CES2 (0.34) | LTA4HCES2PTPN7MEN1FAAH | |
| SCHEMBL22930635 | 0.76 | CES2 (0.52) | CES2MEN1FAAHMAPK1KMT2A | |
| SCHEMBL8134042 | 0.75 | DPP4 (0.34) | SLC7A5DPP4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5869493-A | ANTIVIRALS AGAINST HERPES AND RETROVIRUSES | MEDIVIR AB (SE) | 1999-02-09 | — | — | US | disclosed |