Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PKM | P14618 | 3/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.60 |
| ▸ | PKLR | P30613 | 1/20 | 0.60 |
| ▸ | RAB9A | P51151 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.56 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.56 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.56 |
| ▸ | GAA | P10253 | 2/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | TSHR | P16473 | 2/20 | 0.53 |
| ▸ | CCR6 | P51684 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.52 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8200209 | 0.86 | PKM (0.60) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL8207825 | 0.83 | ADAM17 (0.67) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL6323346 | 0.83 | ADAM17 (0.67) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL6329625 | 0.80 | PKM (0.64) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL8206337 | 0.80 | PKM (0.64) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL8209410 | 0.80 | PKM (0.56) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL21511538 | 0.78 | MAPT (0.51) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL23178943 | 0.78 | PKM (0.75) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL28079047 | 0.77 | PKM (0.63) | PKMSMN1; SMN2NPC1PKLRRAB9A | |
| SCHEMBL8207637 | 0.77 | SMN1; SMN2 (0.59) | PKMSMN1; SMN2NPC1PKLRRAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6121272-A | Bidentate metalloprotease inhibitors | THE PROCTER & GAMBLE COMPANY (US) | 2000-09-19 | — | — | US | disclosed |