Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B1 | P15121 | 2/20 | 0.47 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.39 |
| ▸ | RIPK3 | Q9Y572 | 1/20 | 0.39 |
| ▸ | SENP5 | Q96HI0 | 1/20 | 0.39 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.39 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | ACHE | P22303 | 1/20 | 0.39 |
| ▸ | GSK3B | P49841 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7420131 | 0.91 | AKR1B1 (0.48) | AKR1B1ACKR3MAPTPOLBPTPN1 | |
| SCHEMBL8206201 | 0.90 | MAPT (0.46) | AKR1B1ACKR3MAPTPOLBPTPN1 | |
| SCHEMBL8206839 | 0.90 | MAPT (0.49) | AKR1B1ACKR3MAPTPOLBALDH1A1 | |
| Bicarbonate SCHEMBL7420135 | 0.89 | POLB (0.51) | AKR1B1ACKR3MAPTPOLBALDH1A1 | |
| SCHEMBL8207740 | 0.87 | HPGD (0.42) | MAPTPOLBALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7424534 | 0.83 | MAPT (0.47) | AKR1B1ACKR3MAPTPOLBALDH1A1 | |
| SCHEMBL7430376 | 0.82 | ACKR3 (0.48) | AKR1B1ACKR3MAPTPOLBPTPN1 | |
| SCHEMBL8207774 | 0.82 | LMNA (0.47) | POLBALDH1A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL8207562 | 0.82 | ALDH1A1 (0.43) | MAPTPOLBALDH1A1LMNAKDM4E | |
| SCHEMBL8207861 | 0.81 | LMNA (0.46) | LMNAMEN1KMT2AHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |