SCHEMBL820794

SCHEMBL820794

CCCCCCc1csc(C=O)c1

nearest known ligand 0.44

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 4/20 0.42
HIF1A Q16665 2/20 0.39
EPAS1 Q99814 1/20 0.39
CYP3A4 P08684 2/20 0.39
GPR84 Q9NQS5 2/20 0.39
FAAH O00519 1/20 0.38
MGLL Q99685 1/20 0.38
ESR1 P03372 2/20 0.38
ADRA2A P08913 2/20 0.38
ADORA3 P0DMS8 2/20 0.38
TACR2 P21452 2/20 0.38
SLC6A2 P23975 2/20 0.38
SLC6A4 P31645 2/20 0.38
SLC6A3 Q01959 2/20 0.38
KDM4E B2RXH2 1/20 0.38
ALDH1A1 P00352 1/20 0.38
LMNA P02545 1/20 0.38
SHBG P04278 1/20 0.38
TP53 P04637 1/20 0.38
HSPD1 P10809 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10682713 1.00 PTGS2 (0.42) PTGS2HIF1AEPAS1CYP3A4GPR84
SCHEMBL18825932 0.98 PTGS2 (0.40) PTGS2HIF1AEPAS1CYP3A4GPR84
SCHEMBL18826021 0.93 HPGD (0.36) PTGS2CYP3A4GPR84ALDH1A1HSD17B10
SCHEMBL2494293 0.86 PTGS2 (0.44) PTGS2HIF1ACYP3A4GPR84ESR1
SCHEMBL2494295 0.86 PTGS2 (0.44) PTGS2HIF1ACYP3A4GPR84ESR1
SCHEMBL5803353 0.85 MGLL (0.32) GPR84MGLLALDH1A1
SCHEMBL38662398 0.83 PTGS2 (0.42) PTGS2HIF1ACYP3A4ESR1ADRA2A
SCHEMBL28121498 0.82 HIF1A (0.43) HIF1AEPAS1GPR84
SCHEMBL19513765 0.80 PTGS2 (0.40) PTGS2HIF1ACYP3A4ESR1ADRA2A
SCHEMBL29243279 0.80 CA2 (0.35) GPR84LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 42 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12037531-B2 Photoresponsive high-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2024-07-16 US disclosed
CN-111562729-B Light-responsive low-molecular material, adhesive, toner, and image forming method 柯尼卡美能达株式会社 2024-04-05 CN disclosed
US-11702398-B2 Photoresponsive low-molecular weight material, adhesive, toner, and image forming method Konica Minolta, Inc. (JP) 2023-07-18 US disclosed
CN-111560090-A Photoresponsive polymer material, adhesive, toner and image forming method 柯尼卡美能达株式会社 2020-08-21 CN disclosed
CN-111562729-A Light-responsive low-molecular-weight material, adhesive, toner, and image forming method 柯尼卡美能达株式会社 2020-08-21 CN disclosed
US-20200264530-A1 PHOTORESPONSIVE LOW-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2020-08-20 US disclosed
US-20200263088-A1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD Konica Minolta, Inc. (JP) 2020-08-20 US disclosed
EP-3696249-A1 PHOTORESPONSIVE LOW-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD KONICA MINOLTA, INC. (JP) 2020-08-19 EP disclosed
EP-3696200-A1 PHOTORESPONSIVE HIGH-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD KONICA MINOLTA, INC. (JP) 2020-08-19 EP disclosed
EP-3371291-B1 FORMYLTHIOPHENES AND THEIR USE IN FLAVOR AND FRAGRANCE COMPOSITIONS INT FLAVORS & FRAGRANCES INC (US) 2020-02-19 EP disclosed
US-20120007026-A1 TETRAZINE MONOMERS AND COPOLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES NATIONAL RESEARCH COUNCIL OF CANADA (CA) 2012-01-12 US disclosed
CN-102203160-A Diketopyrrolopyrrole polymers for organic semiconductor devices BASF SE 2011-09-28 CN disclosed
US-20110215313-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2011-09-08 US disclosed
US-20110215313-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2011-09-08 US disclosed
US-20110215313-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2011-09-08 US disclosed
EP-2350160-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2011-08-03 EP disclosed
WO-2010049323-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2010-05-06 WO disclosed
WO-2010049323-A1 DIKETOPYRROLOPYRROLE POLYMERS FOR USE IN ORGANIC SEMICONDUCTOR DEVICES BASF SE (DE) 2010-05-06 WO disclosed
US-6184245-B1 Cyclic ketone derivatives and their medical applications TORAY INDUSTRIES INC. (JP) 2001-02-06 US disclosed
EP-0962456-A1 CYCLIC KETONE DERIVATIVE AND PHARMACEUTICAL USE THEREOF TORAY INDUSTRIES, INC. (JP) 1999-12-08 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120007026-A1 TETRAZINE MONOMERS AND COPOLYMERS FOR USE IN ORGANIC ELECTRONIC DEVICES CCNE1, CCNE2, WEE1 PTGS2 3319/4885HIF1A 3747/4885EPAS1 759/4885
US-11702398-B2 Photoresponsive low-molecular weight material, adhesive, toner, and image forming method ICAM1, CDH1, ACTR5 PTGS2 1646/4885HIF1A 3138/4885EPAS1 1658/4885
US-20200264530-A1 PHOTORESPONSIVE LOW-MOLECULAR WEIGHT MATERIAL, ADHESIVE, TONER, AND IMAGE FORMING METHOD ICAM1, CDH1, ACTR5 PTGS2 1646/4885HIF1A 3138/4885EPAS1 1658/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.