SCHEMBL820873

SCHEMBL820873

O=C(O)c1cccc2c(C(=O)O)c3c(C(=O)O)cccc3c(C(=O)O)c12

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NR4A1 P22736 1/20 0.54
NR4A2 P43354 1/20 0.54
NR4A3 Q92570 1/20 0.54
HSD17B10 Q99714 3/20 0.52
CDC25B P30305 1/20 0.52
ALDH1A1 P00352 5/20 0.50
CYP1A2 P05177 2/20 0.50
ALOX15 P16050 1/20 0.50
PARP1 P09874 1/20 0.49
PRNP P04156 1/20 0.47
AKR1C3 P42330 1/20 0.45
CA12 O43570 2/20 0.44
CA1 P00915 2/20 0.44
CA2 P00918 2/20 0.44
CA7 P43166 2/20 0.44
CA9 Q16790 2/20 0.44
CA14 Q9ULX7 2/20 0.44
KDM4E B2RXH2 3/20 0.43
HPGD P15428 3/20 0.43
TSHR P16473 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471836 0.91 NR4A1 (0.50) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL31401751 0.91 NR4A1 (0.50) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL29549589 0.91 NR4A1 (0.54) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL126721 0.91 NR4A1 (0.54) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL11146438 0.85 TSHR (0.48) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL3936588 0.84 NR4A1 (0.47) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL29549755 0.84 NR4A1 (0.47) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL22996 0.84 NR4A1 (0.47) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL31401818 0.84 NR4A1 (0.47) NR4A1NR4A2NR4A3HSD17B10CDC25B
SCHEMBL8542719 0.83 NR4A1 (0.47) NR4A1NR4A2NR4A3HSD17B10CDC25B

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2569081-B1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PROD & CHEM (US) 2017-08-23 EP disclosed
CN-102946981-B Polymer, polymer film and method for producing same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-11-25 CN disclosed
US-8926733-B2 Polymers, polymer membranes and methods of producing the same AIR PRODUCTS AND CHEMICALS, INC. (US) 2015-01-06 US disclosed
US-8530270-B2 Methods of preparing semiconductive compositions and devices EASTMAN KODAK COMPANY (US) 2013-09-10 US disclosed
US-8411489-B2 Semiconducting devices and methods of preparing EASTMAN KODAK COMPANY (US) 2013-04-02 US disclosed
US-20130047844-A1 POLYMERS, POLYMER MEMBRANES AND METHODS OF PRODUCING THE SAME AIR PRODUCTS AND CHEMICALS, INC. (US) 2013-02-28 US disclosed
CN-102946981-A Polymer, polymer film and method for producing same AIR PROD & CHEM 2013-02-27 CN disclosed
US-8314265-B2 Aromatic amic acids or amic esters and compositions EASTMAN KODAK COMPANY (US) 2012-11-20 US disclosed
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed
WO-2011137133-A2 SEMICONDUCTING DEVICES AND METHODS OF PREPARING EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137137-A1 SEMICONDUCTING ARTICLES EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
WO-2011137139-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS EASTMAN KODAK COMPANY (US) 2011-11-03 WO disclosed
US-20110269966-A1 SEMICONDUCTING ARTICLES CITICORP NORTH AMERICA, INC., AS AGENT 2011-11-03 US disclosed
US-20110269265-A1 METHODS OF PREPARING SEMICONDUCTIVE COMPOSITIONS AND DEVICES KODAK REALTY INC. 2011-11-03 US disclosed
US-20110266523-A1 SEMICONDUCTING DEVICES AND METHODS OF PREPARING BANK OF AMERICA, N.A., AS AGENT 2011-11-03 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20110269966-A1 SEMICONDUCTING ARTICLES ALAD, PORCN, DDC NR4A1 3458/4885NR4A2 3353/4885NR4A3 3740/4885
US-20110269967-A1 AROMATIC AMIC ACIDS OR AMIC ESTERS AND COMPOSITIONS DDC, AADAC, MYOC NR4A1 1358/4885NR4A2 1967/4885NR4A3 2186/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.