Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.43 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | SLC22A2 | O15244 | 1/20 | 0.36 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.36 |
| ▸ | PGR | P06401 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8206102 | 0.90 | MCHR1 (0.41) | HSD11B1OPRK1CHRM2KDM4EALDH1A1 | |
| SCHEMBL8206446 | 0.86 | OPRM1 (0.38) | HSD11B1OPRK1CHRM2CHRM4OPRM1 | |
| SCHEMBL8199247 | 0.85 | AGTR2 (0.42) | OPRK1CHRM2CHRM4OPRM1KCNH2 | |
| SCHEMBL8209731 | 0.81 | HRH1 (0.39) | OPRK1CHRM2CHRM4OPRM1KCNH2 | |
| SCHEMBL8199191 | 0.81 | CHRM2 (0.38) | OPRK1CHRM2CHRM4OPRM1KCNH2 | |
| SCHEMBL8197961 | 0.81 | OPRM1 (0.38) | OPRK1CHRM2CHRM4OPRM1OPRD1 | |
| Hydrochloric Acid SCHEMBL8209836 | 0.81 | AGTR2 (0.47) | OPRK1OPRM1OPRD1 | |
| SCHEMBL8207086 | 0.80 | AOC3 (0.40) | HSD11B1OPRK1CHRM2CHRM4OPRM1 | |
| SCHEMBL8205356 | 0.80 | CHIT1 (0.41) | OPRK1CHRM2CHRM4OPRM1MEN1 | |
| SCHEMBL8199092 | 0.80 | KMT2A (0.40) | OPRK1CHRM2CHRM4OPRM1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | claimed |
| EP-0999205-A1 | AMINOCYCLOALKANE COMPOUNDS | Mitsubishi-Tokyo Pharmaceuticals, Inc. (JP) | 2000-05-10 | — | — | EP | disclosed |