Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGM2 | P21980 | 1/20 | 0.39 |
| ▸ | Q9HBH1 | 1/20 | 0.39 | |
| ▸ | SSTR3 | P32745 | 1/20 | 0.39 |
| ▸ | MGLL | Q99685 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.36 |
| ▸ | GLA | P06280 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 4/20 | 0.35 |
| ▸ | GAA | P10253 | 2/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPY4R | P50391 | 2/20 | 0.33 |
| ▸ | C3AR1 | Q16581 | 1/20 | 0.33 |
| ▸ | CTSL | P07711 | 1/20 | 0.33 |
| ▸ | CTSS | P25774 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL6373661 | 0.88 | PDF (0.48) | PDFSSTR3MGLLSMN1; SMN2ALDH1A1 | |
| SCHEMBL5522251 | 0.83 | NOD1 (0.42) | NPY4RC3AR1CTSLCTSS | |
| Hydrochloric Acid SCHEMBL9763814 | 0.82 | PDF (0.46) | PDFSSTR3MGLLSMN1; SMN2ALDH1A1 | |
| Acetic Acid SCHEMBL9603824 | 0.81 | C3AR1 (0.39) | TGM2NPY4RC3AR1CTSLCTSS | |
| SCHEMBL38651683 | 0.79 | PDF (0.51) | PDFSSTR3SMN1; SMN2ALDH1A1MAPT | |
| Hydrochloric Acid SCHEMBL9763741 | 0.79 | PDF (0.44) | PDFSSTR3MAPTKDM4E | |
| SCHEMBL29713645 | 0.77 | SIRT5 (0.46) | PDFSSTR3NPY4R | |
| Hydrochloric Acid SCHEMBL3503087 | 0.77 | SIRT5 (0.51) | TGM2 | |
| 4-Nitroaniline SCHEMBL17870565 | 0.77 | TGM2 (0.40) | TGM2ALDH1A1MAPTPKMNPY4R | |
| Hydrochloric Acid SCHEMBL9763347 | 0.76 | PDF (0.44) | PDFSSTR3SMN1; SMN2ALDH1A1GLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6037334-A | INHIBITORS OF FACTOR XA THAT CAN BE USED TO PREVENT DISEASES SUCH ASTHROMBOSIS, APOPLEXY, CORONARY INFARCTION, INFLAMMATIONS, AND ARTERIOSCLEROSIS | ROCHE DIAGNOSTICS GMBH (DE) | 2000-03-14 | — | — | US | disclosed |
| EP-0938489-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1999-09-01 | — | — | EP | disclosed |
| EP-0937723-A1 | Novel sulfonamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |
| EP-0937711-A1 | Thiobenzamides, process for their preparation and medicaments containing them | Roche Diagnostics GmbH (DE) | 1999-08-25 | — | — | EP | disclosed |
| EP-0846115-A1 | NEW CYCLIC GUANIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | Roche Diagnostics GmbH (DE) | 1998-06-10 | — | — | EP | disclosed |
| WO-1998022483-A1 | NEW PHOSPHONATES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | ROCHE DIAGNOSTICS GMBH (DE) | 1998-05-28 | — | — | WO | disclosed |
| WO-1997008165-A1 | NEW CYCLIC GUANIDINES, PROCESS FOR PREPARING THE SAME AND MEDICAMENTS | BOEHRINGER MANNHEIM GMBH (DE) | 1997-03-06 | — | — | WO | disclosed |