Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | FNTA | P49354 | 4/20 | 0.32 |
| ▸ | FNTB | P49356 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 2/20 | 0.32 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA9 | Q16790 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209147 | 0.88 | FNTA (0.40) | NAMPTKMT2AFNTAFNTBPGGT1B | |
| SCHEMBL8198280 | 0.83 | FNTA (0.46) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8206389 | 0.83 | FNTA (0.46) | FNTAFNTBPGGT1BALDH1A1 | |
| SCHEMBL8198655 | 0.81 | FNTA (0.41) | FNTAFNTB | |
| SCHEMBL8227708 | 0.80 | CYP19A1 (0.41) | FNTAFNTB | |
| SCHEMBL8205624 | 0.78 | CA2 (0.46) | SMN1; SMN2KMT2ANPSR1FNTAFNTB | |
| SCHEMBL8199776 | 0.77 | FNTA (0.49) | FNTAFNTB | |
| SCHEMBL8211056 | 0.76 | FNTA (0.40) | NAMPTSMN1; SMN2FNTAFNTBGAA | |
| SCHEMBL8207254 | 0.76 | FNTA (0.47) | FNTAFNTB | |
| SCHEMBL8273539 | 0.75 | GAA (0.43) | NAMPTSMN1; SMN2KMT2AGAAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0975603-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 2000-02-02 | — | — | EP | disclosed |
| WO-1998032741-A1 | INHIBITORS OF FARNESYL PROTEIN TRANSFERASE | ZENECA LIMITED (GB) | 1998-07-30 | — | — | WO | disclosed |