Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | AQP1 | P29972 | 1/20 | 0.33 |
| ▸ | AADAT | Q8N5Z0 | 1/20 | 0.32 |
| ▸ | NOS3 | P29474 | 1/20 | 0.32 |
| ▸ | FABP4 | P15090 | 4/20 | 0.31 |
| ▸ | FABP3 | P05413 | 1/20 | 0.31 |
| ▸ | HTR1A | P08908 | 2/20 | 0.30 |
| ▸ | HTR7 | P34969 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4732072 | 0.77 | TDP1 (0.40) | TDP1L3MBTL1AQP1FABP4FABP3 | |
| SCHEMBL4731714 | 0.77 | TDP1 (0.40) | TDP1L3MBTL1AQP1FABP4FABP3 | |
| SCHEMBL8258102 | 0.76 | AQP1 (0.42) | TDP1L3MBTL1AQP1HTR1AHTR7 | |
| SCHEMBL8255634 | 0.76 | AQP1 (0.42) | TDP1L3MBTL1AQP1HTR1AHTR7 | |
| SCHEMBL4621299 | 0.76 | AQP1 (0.42) | TDP1L3MBTL1AQP1HTR1AHTR7 | |
| SCHEMBL4932578 | 0.75 | L3MBTL1 (0.39) | TDP1L3MBTL1AQP1FABP4FABP3 | |
| Hydrochloric Acid SCHEMBL4934942 | 0.75 | AQP1 (0.41) | TDP1L3MBTL1AQP1HTR1AHTR7 | |
| SCHEMBL4729890 | 0.75 | SMN1; SMN2 (0.41) | TDP1L3MBTL1FABP4FABP3 | |
| Hydrochloric Acid SCHEMBL4621884 | 0.75 | AQP1 (0.41) | TDP1L3MBTL1AQP1HTR1AHTR7 | |
| SCHEMBL8213736 | 0.75 | SMN1; SMN2 (0.41) | TDP1L3MBTL1FABP4FABP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008052087-A1 | CHROMANE DERIVATIVES AND USES THEREOF | WYETH (US) | 2008-05-02 | — | — | WO | disclosed |