SCHEMBL820991

SCHEMBL820991

FC(F)(F)C(Cl)(Cl)C(Cl)(Cl)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL857073 0.89 ALDH1A1 (0.30) ALDH1A1LMNACYP2E1TSHR
SCHEMBL1413774 0.87 LMNA (0.32) LMNA
SCHEMBL8679362 0.87 LMNA (0.32) LMNA
SCHEMBL8676620 0.87
SCHEMBL9120453 0.83 LMNA (0.37) LMNA
SCHEMBL8676768 0.83
SCHEMBL3860300 0.83 LMNA (0.37) LMNA
SCHEMBL674470 0.83
SCHEMBL9101338 0.80
SCHEMBL1223429 0.80

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 72 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119081699-A Process for producing alkane 大金工业株式会社 2024-12-06 CN claimed
US-20080108749-A1 Fluoropolymer nanoemulsions NANOMAX TECHNOLOGY COMPANY LIMITED 2008-05-08 US claimed
EP-1028101-B1 Process for the CFC-113a dimerisation SOLVAY SOLEXIS SPA (IT) 2003-04-09 EP claimed
EP-1262470-A1 Process for the (CFC-113a) dimerization Ausimont S.p.A. (IT) 2002-12-04 EP claimed
US-6348634-B1 REDUCTIVE DIMERIZATION PROCESS WITH HYDROGEN; FORMING 1,1,1,4,4,4-HEXAFLUORO-2,2,3,3-TETRACHLORO-BUTANE AND 1,1,1,4,4,4-HEXAFLUORO-2,3-DICHLOROBUTENE USING RUTHENIUM CATALYST SUPPORTED ON GRAPHITIZED CARBON OR ALUMINUM FLUORIDE AUSIMONT S.P.A. (IT) 2002-02-19 US claimed
EP-1028101-A1 Process for the CFC-113a dimerisation Ausimont S.p.A. (IT) 2000-08-16 EP claimed
WO-1999000345-A1 PROCESS FOR THE PREPARATION OF 1,1,2,3,3,4-HEXAFLUOROBUTANE ALLIEDSIGNAL INC. (US) 1999-01-07 WO claimed
US-5824826-A Process for the preparation of 1,1,2,3,3,4-hexafluorobutane ALLIEDSIGNAL INC. (US) 1998-10-20 US claimed
EP-0401722-B1 Use of blowing compositions DAIKIN IND LTD (JP) 1996-04-24 EP claimed
US-12583992-B2 Composite body AGC Inc. (JP) 2026-03-24 US disclosed
EP-4269376-A1 HYDROHALOOLEFIN COMPOSITION AGC INC. (JP) 2023-11-01 EP disclosed
US-20230323177-A1 HYDROHALOOLEFIN COMPOSITION AGC Inc. (JP) 2023-10-12 US disclosed
CN-114008135-B Composition for forming fluorine-containing sealing material 大金工业株式会社 2023-04-11 CN disclosed
US-11578232-B2 Super-liquid-repellent coating film and curable composition for forming super-liquid-repellent coating film DAIKIN INDUSTRIES, LTD. (JP) 2023-02-14 US disclosed
WO-1994006742-A1 PROCESS FOR PREPARING PERHALOACYL CHLORIDES E.I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-31 WO disclosed
US-5296640-A Oxidation E. I. DU PONT DE NEMOURS AND COMPANY (US) 1994-03-22 US disclosed
EP-0315783-B1 PROCESS FOR THE PREPARATION OF FLUORINATED C-4 TO C-6 HYDROCARBONS AND FLUORINATED CYCLIC HYDROCARBONS, AND THE USE OF FLUORINATED C-4 TO C-6 HYDROCARBONS AS PROPELLANTS AND WORKING FLUIDS IN HEAT PUMP SYSTEMS BAYER AG (DE) 1991-06-12 EP disclosed
US-4954666-A Process for preparing fluorinated C4 to C6 hydrocarbons and novel cyclic fluorinated hydrocarbons and their use as propellant gas and working fluid for heat pump systems BAYER AKTIENGESELLSCHAFT (DE) 1990-09-04 US disclosed
US-4902839-A Process for preparing fluorinated C4 to C6 hydrocarbons and novel cyclic fluorinated hydrocarbons and their use as propellant gas and working fluid for heat pump systems BAYER AKTIENGESELLSCHAFT (DE) 1990-02-20 US disclosed
EP-0315783-A1 Process for the preparation of fluorinated C-4 to C-6 hydrocarbons and fluorinated cyclic hydrocarbons, and the use of fluorinated C-4 to C-6 hydrocarbons as propellants and working fluids in heat pump systems BAYER AG (DE) 1989-05-17 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12583992-B2 Composite body FIP1L1, PCBP1, POT1 ALDH1A1 1719/4885LMNA 2880/4885CYP2E1 647/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.