SCHEMBL857073

SCHEMBL857073

FC(F)(F)C(Cl)(Cl)C(F)(F)F

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.30
LMNA P02545 1/20 0.30
CYP2E1 P05181 1/20 0.30
TSHR P16473 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL820991 0.89 ALDH1A1 (0.30) ALDH1A1LMNACYP2E1TSHR
SCHEMBL1904473 0.80
SCHEMBL1223429 0.80
SCHEMBL9101338 0.80
SCHEMBL8679362 0.77 LMNA (0.32) LMNA
SCHEMBL1413774 0.77 LMNA (0.32) LMNA
SCHEMBL8676620 0.77
SCHEMBL2049790 0.77
SCHEMBL674470 0.74
SCHEMBL9120453 0.74 LMNA (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 293 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250382247-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2025-12-18 US claimed
CN-119191948-A Hexafluoroacetone tris method for preparing hydrate 湖南有色郴州氟化学有限公司 2024-12-27 CN claimed
EP-4357328-A2 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE The Chemours Company FC, LLC (US) 2024-04-24 EP claimed
US-20230052956-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2023-02-16 US claimed
EP-4093721-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE The Chemours Company FC, LLC (US) 2022-11-30 EP claimed
CN-115003648-A (E) Synthesis of (E) -1, 1, 1, 4, 5, 5, 5-heptafluoro-4- (trifluoromethyl) pent-2-ene 科慕埃弗西有限公司 2022-09-02 CN claimed
WO-2021150801-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE THE CHEMOURS COMPANY FC, LLC (US) 2021-07-29 WO claimed
EP-3147274-B1 PROCESSES FOR SEPARATION OF 3,3,3-TRIFLUOROPROPENE AND HYDROGEN FLUORIDE CHEMOURS CO FC LLC (US) 2018-09-05 EP claimed
EP-3147274-A1 PROCESSES FOR SEPARATION OF 3,3,3-TRIFLUOROPROPENE AND HYDROGEN FLUORIDE The Chemours Company FC, LLC (US) 2017-03-29 EP claimed
US-9000238-B2 Processes for separation of fluoroolefins from hydrogen fluoride by azeotropic distillation E I DU PONT DE NEMOURS AND COMPANY (US) 2015-04-07 US claimed
US-6291729-B1 Halofluorocarbon hydrogenolysis E. I. DU PONT DE NEMOURS AND COMPANY 2001-09-18 US claimed
EP-0796235-B1 PRODUCTION OF 2-CHLORO-2-HYDROHEXAFLUOROPROPANE AND AZEOTROPES THEREOF WITH HF DU PONT (US) 1999-06-09 EP claimed
US-5902911-A Production of 2-chloro-2-hydrohexafluoropropane and azeotropes thereof with HF E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-05-11 US claimed
EP-0796235-A1 PRODUCTION OF 2-CHLORO-2-HYDROHEXAFLUOROPROPANE AND AZEOTROPES THEREOF WITH HF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1997-09-24 EP claimed
WO-1996017813-A1 HALOFLUOROCARBON HYDROGENOLYSIS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-06-13 WO claimed
WO-1996017815-A1 PRODUCTION OF 2-CHLORO-2-HYDROHEXAFLUOROPROPANE AND AZEOTROPES THEREOF WITH HF E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-06-13 WO claimed
US-5481051-A 2,2-dichlorohexafluoropropane hydrogenolysis E. I. DU PONT DE NEMOURS AND COMPANY (US) 1996-01-02 US claimed
EP-0449977-A1 IMPROVED HYDROGENOLYSIS/DEHYDROHALOGENATION PROCESS. DU PONT (US) 1991-10-09 EP claimed
CN-1044648-A Improved hydrogenolysis/process for dehydrohalogenation DU PONT (US) 1990-08-15 CN claimed
WO-1990008748-A1 IMPROVED HYDROGENOLYSIS/DEHYDROHALOGENATION PROCESS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1990-08-09 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230052956-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE ECE1, ENO1, GALE ALDH1A1 288/4885LMNA 2246/4885CYP2E1 34/4885
US-20250382247-A1 SYNTHESIS OF (E)-1,1,1,4,5,5,5-HEPTAFLUORO-4-(TRIFLUOROMETHYL)PENT-2-ENE ECE1, ENO1, GALE ALDH1A1 354/4885LMNA 2157/4885CYP2E1 44/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.