SCHEMBL8679362

SCHEMBL8679362

FC(F)(F)C(F)(F)C(Cl)(Cl)C(F)(F)F

nearest known ligand 0.32

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1413774 0.92 LMNA (0.32) LMNA
SCHEMBL3860300 0.88 LMNA (0.37) LMNA
SCHEMBL8984129 0.87 LMNA (0.33) LMNA
SCHEMBL3686958 0.87 LMNA (0.33) LMNA
SCHEMBL820991 0.87 ALDH1A1 (0.30) LMNA
SCHEMBL9635592 0.80 LMNA (0.30) LMNA
SCHEMBL1898494 0.80 LMNA (0.30) LMNA
SCHEMBL9123202 0.80 LMNA (0.37) LMNA
SCHEMBL674470 0.80
SCHEMBL9120453 0.80 LMNA (0.37) LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5756869-A Method of preparing hydrofluorocarbon CENTRAL GLASS COMPANY LIMITED (JP) 1998-05-26 US disclosed
CN-1035250-C Process for preparing fluorinated compound DUIKIN IND LTD (JP) 1997-06-25 CN disclosed
EP-0518353-B1 Process for preparation fluorinated compound DAIKIN IND LTD (JP) 1996-01-24 EP disclosed
US-5326913-A Process for preparing fluorinated compound DAIKIN INDUSTRIES LTD. (JP) 1994-07-05 US disclosed
CN-1067879-A The method for preparing fluorinated compound DUIKIN IND LTD (JP) 1993-01-13 CN disclosed
EP-0518353-A2 Process for preparation fluorinated compound DAIKIN INDUSTRIES, LIMITED (JP) 1992-12-16 EP disclosed
CN-86101978-B Preparation method of crosslinkable fluorine-containing copolymer 旭化成工业株式会社 1988-09-14 CN disclosed
CN-86101978-A A kind of preparation method of crosslinkable fluorinated copolymer 1987-09-16 CN disclosed