Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.56 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 1/20 | 0.50 |
| ▸ | NAMPT | P43490 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8207980 | 0.90 | GAA (0.55) | KMT2AAPEX1LMNA | |
| SCHEMBL8206949 | 0.87 | LMNA (0.57) | KMT2AALDH1A1APEX1LMNASMN1; SMN2 | |
| SCHEMBL8210433 | 0.86 | KMT2A (0.55) | KMT2AALDH1A1APEX1LMNASMN1; SMN2 | |
| SCHEMBL7893101 | 0.82 | ALDH1A1 (0.56) | KMT2AALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL7430348 | 0.81 | ALDH1A1 (0.53) | KMT2AALDH1A1APEX1LMNASMN1; SMN2 | |
| SCHEMBL8207487 | 0.80 | KMT2A (0.51) | KMT2AALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8210407 | 0.79 | KMT2A (0.53) | KMT2AALDH1A1LMNASMN1; SMN2L3MBTL1 | |
| SCHEMBL8212496 | 0.79 | GAA (0.56) | KMT2AAPEX1LMNA | |
| SCHEMBL7892988 | 0.78 | NR1H4 (0.58) | KMT2AALDH1A1APEX1SMN1; SMN2RECQL | |
| SCHEMBL8200517 | 0.78 | SMN1; SMN2 (0.53) | KMT2AALDH1A1APEX1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6143777-A | ENZYME INHIBITORS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2000-11-07 | — | — | US | disclosed |