Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | P2RX4 | Q99571 | 1/20 | 0.38 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.36 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | ADAM10 | O14672 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP3 | P08254 | 1/20 | 0.36 |
| ▸ | MMP9 | P14780 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | BRD4 | O60885 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8211547 | 0.72 | ATM (0.47) | KIF11MEN1KMT2AP2RX4ATM | |
| SCHEMBL3262109 | 0.71 | KDM4E (0.47) | KIF11MEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL3628702 | 0.68 | P2RX4 (0.46) | MEN1KMT2AP2RX4SMN1; SMN2 | |
| SCHEMBL31073550 | 0.64 | KCNH2 (0.56) | MEN1KMT2ASMN1; SMN2ADAM10MMP2 | |
| SCHEMBL2391310 | 0.62 | HTT (0.40) | MEN1KMT2ASLC6A2SLC6A4SLC6A3 | |
| SCHEMBL31233183 | 0.62 | MEN1 (0.52) | KIF11MEN1KMT2ASLC6A2SLC6A4 | |
| SCHEMBL10756064 | 0.62 | ATM (0.41) | MEN1KMT2AP2RX4ATMSMN1; SMN2 | |
| SCHEMBL14523185 | 0.62 | SCN9A (0.43) | MEN1KMT2AATMSMN1; SMN2KDM4E | |
| SCHEMBL10002512 | 0.61 | RIPK1 (0.64) | MEN1KMT2A | |
| SCHEMBL19493611 | 0.61 | RAB9A (0.62) | MEN1KMT2AATMSMN1; SMN2ADAM10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010012812-A1 | BENZAZEPINES AND BENZAZOCINES AS SIGMA-RECEPTOR LIGANDES | Westfälische Wilhelms Universität Münster (DE) | 2010-02-04 | — | — | WO | disclosed |