Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR1 | P21453 | 1/20 | 0.42 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.42 |
| ▸ | GRM2 | Q14416 | 3/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | ACE | P12821 | 2/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | AMPD2 | Q01433 | 1/20 | 0.37 |
| ▸ | KDM1A | O60341 | 3/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | GRM3 | Q14832 | 2/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 3/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | GRM6 | O15303 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8209192 | 0.85 | MMP13 (0.49) | S1PR5KDM1AMAOAMAOB | |
| SCHEMBL8209631 | 0.77 | S1PR5 (0.51) | S1PR5KDM1AMAOAMAOB | |
| SCHEMBL8209566 | 0.77 | POLB (0.45) | ALDH1A1KDM1AMAOAMAOBMEN1 | |
| SCHEMBL8209387 | 0.74 | S1PR5 (0.42) | S1PR5FFAR1ALDH1A1MAOAMAOB | |
| SCHEMBL8211740 | 0.66 | ROCK2 (0.38) | S1PR1GRM2GRM3 | |
| SCHEMBL8213082 | 0.66 | MEN1 (0.44) | ALDH1A1MEN1KMT2A | |
| SCHEMBL2837466 | 0.66 | ACE (0.54) | S1PR1S1PR5ACE | |
| SCHEMBL23633187 | 0.65 | FFAR1 (0.58) | FFAR1ALDH1A1MAOAMAOBMEN1 | |
| Urea SCHEMBL2006220 | 0.65 | FFAR1 (0.62) | FFAR1ALDH1A1MAOAMAOB | |
| Carbamic Acid SCHEMBL2222080 | 0.65 | FFAR1 (0.62) | FFAR1ALDH1A1MAOAMAOB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6114361-A | INHIBITORS OF MATRIX METALLOPROTEINASES AND REPROLYSIN; ADMINISTERING TO TREAT CONDITIONS WHICH CAN BE TREATED BY THE INHIBITION OF THESE ENZYMES | PFIZER INC. (US) | 2000-09-05 | — | — | US | claimed |