Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKT1 | P31749 | 2/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | AKT2 | P31751 | 1/20 | 0.53 |
| ▸ | RPS6KA3 | P51812 | 3/20 | 0.47 |
| ▸ | AURKA | O14965 | 1/20 | 0.47 |
| ▸ | CDK1 | P06493 | 1/20 | 0.47 |
| ▸ | LYN | P07948 | 1/20 | 0.47 |
| ▸ | PIM1 | P11309 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 1/20 | 0.47 |
| ▸ | PRKACA | P17612 | 1/20 | 0.47 |
| ▸ | RPS6KB1 | P23443 | 1/20 | 0.47 |
| ▸ | CDK2 | P24941 | 1/20 | 0.47 |
| ▸ | MARK3 | P27448 | 1/20 | 0.47 |
| ▸ | GSK3B | P49841 | 1/20 | 0.47 |
| ▸ | PRKCZ | Q05513 | 1/20 | 0.47 |
| ▸ | PRKCD | Q05655 | 1/20 | 0.47 |
| ▸ | ERBB4 | Q15303 | 1/20 | 0.47 |
| ▸ | CDC42BPA | Q5VT25 | 1/20 | 0.47 |
| ▸ | MARK2 | Q7KZI7 | 1/20 | 0.47 |
| ▸ | AKT3 | Q9Y243 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10981794 | 0.98 | AKT1 (0.52) | AKT1LMNAAKT2RPS6KA3AURKA | |
| SCHEMBL6601415 | 0.85 | PTGS2 (0.59) | METAP2 | |
| SCHEMBL7264282 | 0.82 | TGFBR1 (0.59) | LMNAL3MBTL1CYP1A2TGFBR1ATM | |
| SCHEMBL4049176 | 0.81 | MAPT (0.47) | RPS6KA3CYP1A2TGFBR1METAP2HSD17B10 | |
| SCHEMBL9824714 | 0.80 | NISCH (0.51) | AKT1LMNAAKT2RPS6KA3AURKA | |
| SCHEMBL15579660 | 0.79 | RPS6KA3 (0.53) | AKT1LMNAAKT2RPS6KA3AURKA | |
| SCHEMBL3055446 | 0.79 | AKT1 (0.52) | AKT1LMNAAKT2RPS6KA3AURKA | |
| SCHEMBL2511846 | 0.79 | LMNA (0.47) | AKT1LMNAAKT2AURKAFGFR1 | |
| SCHEMBL11403774 | 0.79 | CYP1A2 (0.44) | AKT1LMNAAKT2RPS6KA3L3MBTL1 | |
| SCHEMBL10558188 | 0.79 | HPGD (0.46) | AKT1LMNAAKT2L3MBTL1CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 13 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230095836-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION | 2023-03-30 | — | — | US | disclosed |
| EP-4103554-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2022-12-21 | — | — | EP | disclosed |
| CN-115087639-A | Substituted 5, 6-diphenyl-3 (2H) -pyridazinones for use as fungicides | FMC公司 | 2022-09-20 | — | — | CN | disclosed |
| WO-2021163519-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | FMC CORPORATION (US) | 2021-08-19 | — | — | WO | disclosed |
| WO-2008019266-A2 | ACYCLIC, PYRIDAZINONE-DERIVED HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |
| WO-2008019303-A2 | PYRIDAZINONYL MACROCYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-14 | — | — | WO | disclosed |
| EP-0442448-A2 | Heterocyclic carboxylic acids and esters | Bristol-Myers Squibb Company (US) | 1991-08-21 | — | — | EP | disclosed |
| US-4992439-A | Pyridazine carboxylic acids and esters | BRISTOL-MYERS SQUIBB COMPANY (US) | 1991-02-12 | — | — | US | disclosed |
| US-4545810-A | Herbicidal and plant growth regulant diphenylpyridazinones | SDS BIOTECH CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| US-4545810-A | Herbicidal and plant growth regulant diphenylpyridazinones | SDS BIOTECH CORPORATION (US) | 1985-10-08 | — | — | US | disclosed |
| WO-1982000402-A1 | HERBICIDAL AND PLANT GROWTH REGULANT DIPHENYLPYRIDAZINONES | DIAMOND SHAMROCK CORP (US) | 1982-02-18 | — | — | WO | disclosed |
| EP-0046069-A1 | Herbicidal and plant growth regulant diphenylpyridazinones | DIAMOND SHAMROCK CORPORATION (US) | 1982-02-17 | — | — | EP | disclosed |
| EP-0046069-A1 | Herbicidal and plant growth regulant diphenylpyridazinones | DIAMOND SHAMROCK CORPORATION (US) | 1982-02-17 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230095836-A1 | SUBSTITUTED 5,6-DIPHENYL-3(2H)-PYRIDAZINONES FOR USE AS FUNGICIDES | PNPO, CBR3, CYP2D6 | AKT1 1534/4885LMNA 3832/4885AKT2 1845/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.