Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | FPR2 | P25090 | 1/20 | 0.31 |
| ▸ | PROKR1 | Q8TCW9 | 1/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | THRB | P10828 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4381279 | 0.78 | PKM (0.49) | MEN1KMT2APKMCYP2C9ALDH1A1 | |
| SCHEMBL4377766 | 0.76 | NR3C1 (0.40) | MEN1KMT2APKMCYP2C9ALDH1A1 | |
| SCHEMBL4392624 | 0.75 | GAA (0.40) | MEN1KMT2APKMCYP2C9ALDH1A1 | |
| SCHEMBL4382795 | 0.75 | THRB (0.43) | MEN1KMT2APKMALDH1A1CYP1A2 | |
| SCHEMBL4383070 | 0.75 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4387340 | 0.75 | USP30 (0.37) | MEN1KMT2ACYP2C9CYP1A2CYP2C19 | |
| SCHEMBL4390159 | 0.74 | MEN1 (0.49) | MEN1KMT2ACYP2C9ALDH1A1LMNA | |
| SCHEMBL4391478 | 0.74 | PKM (0.52) | MEN1KMT2APKMALDH1A1LMNA | |
| SCHEMBL4382549 | 0.73 | TP53 (0.46) | PKMPOLBLMNA | |
| SCHEMBL4385272 | 0.73 | PKM (0.54) | KMT2APKMALDH1A1POLBLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008008398-A2 | OXIME COMPOUNDS AND THE USE THEREOF | SHIONOGI & CO., LTD. (JP) | 2008-01-17 | — | — | WO | disclosed |