Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 5/20 | 0.35 |
| ▸ | RAB9A | P51151 | 5/20 | 0.35 |
| ▸ | CASP1 | P29466 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.35 |
| ▸ | DNTT | P04053 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 5/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.34 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.34 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.34 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 4/20 | 0.33 |
| ▸ | ATM | Q13315 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | TSHR | P16473 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL820100 | 0.90 | ALDH1A1 (0.42) | RAB9AALDH1A1L3MBTL1MAPK1KDM4E | |
| SCHEMBL818518 | 0.82 | CYP1A2 (0.36) | MAPK1CHRM2CHRM4CHRM3TSHR | |
| SCHEMBL1298046 | 0.75 | ALDH1A1 (0.54) | ALDH1A1L3MBTL1MAPK1CHRM2CHRM4 | |
| SCHEMBL14473946 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL12293872 | 0.74 | ALDH1A1 (0.42) | ALDH1A1CHRM2CHRM4CHRM5CHRM1 | |
| SCHEMBL820967 | 0.74 | CA1 (0.37) | ALDH1A1KDM4EHPGDMAPTLMNA | |
| SCHEMBL7669797 | 0.73 | ALDH1A1 (0.52) | RAB9AALDH1A1L3MBTL1MAPK1CHRM2 | |
| SCHEMBL7669796 | 0.73 | ALDH1A1 (0.52) | RAB9AALDH1A1L3MBTL1MAPK1CHRM2 | |
| SCHEMBL818820 | 0.72 | CYP3A4 (0.47) | ALDH1A1L3MBTL1MAPK1ATMRECQL | |
| SCHEMBL14878543 | 0.72 | ALDH1A1 (0.36) | ALDH1A1L3MBTL1MAPK1KDM4ECHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8426639-B2 | Preparation of trans, trans muconic acid and trans, trans muconates | Amyris, Inc. (US) | 2013-04-23 | — | — | US | disclosed |
| US-8415496-B2 | Biobased polyesters | Amyris, Inc. | 2013-04-09 | — | — | US | disclosed |
| US-8415496-B2 | Biobased polyesters | Amyris, Inc. | 2013-04-09 | — | — | US | disclosed |
| US-8367859-B2 | Cyclohexane 1,4 carboxylates | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| US-8367858-B2 | Terephthalic and trimellitic based acids and carboxylate derivatives thereof | Amyris, Inc. (US) | 2013-02-05 | — | — | US | disclosed |
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288263-A1 | BIOBASED POLYESTERS | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | DRATHS CORPORATION (US) | 2011-11-24 | — | — | US | disclosed |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | DRATHS CORPORATION (US) | 2011-11-17 | — | — | US | disclosed |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | DRATHS CORPORATION (US) | 2010-12-16 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110288310-A1 | CYCLOHEXANE 1,4 CARBOXYLATES | CNR2, CBR1, CCR4 | NPC1 1875/4885RAB9A 3530/4885CASP1 1202/4885 |
| US-20110282078-A1 | CYCLOHEXENE 1,4 -CARBOXYLATES | CBR1, MCM4, CCR4 | NPC1 1958/4885RAB9A 3735/4885CASP1 1423/4885 |
| US-20110288311-A1 | NOVEL TEREPHTHALIC AND TRIMELLITIC BASED ACIDS AND CARBOXYLATE DERIVATIVES THEREOF | TRIM4, DDT, PICALM | NPC1 3945/4885RAB9A 4828/4885CASP1 3030/4885 |
| US-20100314243-A1 | PREPARATION OF TRANS,TRANS MUCONIC ACID AND TRANS,TRANS MUCONATES | MUC1, FUT6, ST6GAL1 | NPC1 1091/4885RAB9A 604/4885CASP1 4139/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.