Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7968627 | 0.83 | CHRNB2 (0.31) | — | |
| SCHEMBL13784844 | 0.82 | GABRR1 (0.31) | — | |
| SCHEMBL15943103 | 0.82 | OPRD1 (0.31) | OPRD1 | |
| SCHEMBL14369479 | 0.79 | — | — | |
| SCHEMBL13149375 | 0.79 | OPRD1 (0.30) | OPRD1 | |
| SCHEMBL8250376 | 0.79 | GSK3B (0.33) | — | |
| SCHEMBL12816825 | 0.79 | SLC6A3 (0.33) | — | |
| SCHEMBL23095736 | 0.76 | — | — | |
| SCHEMBL1355394 | 0.75 | — | — | |
| SCHEMBL23470770 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2509981-B1 | INHIBITORS OF DIACYLGLYCEROL ACYLTRANSFERASE | LILLY CO ELI (US) | 2014-08-06 | — | — | EP | disclosed |
| WO-2008010985-A2 | PHOSPHORUS DERIVATIVES AS HISTONE DEACETYLASE INHIBITORS | MERCK & CO., INC. (US) | 2008-01-24 | — | — | WO | disclosed |
| CN-1158287-C | Benzothieno [3,2-c]pyridines as alpha 2-antagonists | ղɭҩҵ����˾ | 2004-07-21 | — | — | CN | disclosed |
| CN-1154646-C | As α2Benzisoxazoles and phenones as antagonists | ղɭҩҵ����˾ | 2004-06-23 | — | — | CN | disclosed |
| CN-1131868-C | Tricyclic delta 3-piperidines as pharmaceuticals | JANSSEN PHARMACEUTICA N.V. (BE) | 2003-12-24 | — | — | CN | disclosed |
| CN-1131230-C | Tricyclic delta 3-piperidines as alpha 2-antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2003-12-17 | — | — | CN | disclosed |
| CN-1332744-A | As α2Tricyclic delta 3-piperidines as antagonists | JANSSEN PHARMACEUTICA NV (BE) | 2002-01-23 | — | — | CN | disclosed |
| CN-1331692-A | Benzisozazoles and phenones as alpha antagonist | JANSSEN PHARMACEUTICA NV (BE) | 2002-01-16 | — | — | CN | disclosed |
| CN-1321159-A | As α2Benzothieno [3, 2-c ] antagonists]Pyridine compound | JANSSEN PHARMACEUTICA NV (BE) | 2001-11-07 | — | — | CN | disclosed |
| CN-1321158-A | Tricyclic delta 3-piperidines as pharmaceuticals | JANSSEN PHARMACEUTICA NV (BE) | 2001-11-07 | — | — | CN | disclosed |