Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FYN | P06241 | 2/20 | 0.42 |
| ▸ | MET | P08581 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | ESR1 | P03372 | 1/20 | 0.37 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | CYP2A6 | P11509 | 3/20 | 0.35 |
| ▸ | ESRRG | P62508 | 1/20 | 0.35 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.35 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.35 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.35 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.34 |
| ▸ | CYP2E1 | P05181 | 1/20 | 0.34 |
| ▸ | CYP2B6 | P20813 | 1/20 | 0.34 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8212283 | 0.83 | CYP2A6 (0.53) | FYNMAPTCYP2A6PTGER1CYP2E1 | |
| SCHEMBL8221922 | 0.81 | GABRA1 (0.46) | KMT2AMEN1CYP2A6 | |
| SCHEMBL3270763 | 0.79 | BRAF (0.50) | KMT2AUSP2MAPTNPSR1 | |
| SCHEMBL8220878 | 0.75 | ALOX15 (0.50) | KMT2AMEN1ESR1ESR2USP2 | |
| SCHEMBL649500 | 0.73 | CYP2A6 (0.58) | FYNKMT2AMEN1HSP90AA1ESR1 | |
| SCHEMBL7448864 | 0.73 | CYP2A6 (0.58) | FYNKMT2AMEN1HSP90AA1ESR1 | |
| SCHEMBL8213534 | 0.73 | ESR1 (0.40) | HSP90AA1ESR1ESR2CYP2A6 | |
| SCHEMBL28764321 | 0.72 | CYP2A6 (0.56) | FYNKMT2AMEN1HSP90AA1ESR1 | |
| SCHEMBL5729548 | 0.68 | KMT2A (0.43) | FYNKMT2AMEN1HSP90AA1ESR1 | |
| SCHEMBL8214582 | 0.68 | KMT2A (0.40) | KMT2AMEN1ESR1ESR2USP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008021871-A2 | TRIAZOLYL ACYCLIC HEPATITIS C SERINE PROTEASE INHIBITORS | ENANTA PHARMACEUTICALS, INC. (US) | 2008-02-21 | — | — | WO | disclosed |