Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2A6 | P11509 | 3/20 | 0.58 |
| ▸ | CYP2E1 | P05181 | 2/20 | 0.58 |
| ▸ | CYP2B6 | P20813 | 2/20 | 0.58 |
| ▸ | ESR1 | P03372 | 3/20 | 0.55 |
| ▸ | ESR2 | Q92731 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.50 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.48 |
| ▸ | ERN1 | O75460 | 1/20 | 0.48 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.48 |
| ▸ | CYP17A1 | P05093 | 1/20 | 0.47 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.47 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.47 |
| ▸ | MMP3 | P08254 | 1/20 | 0.46 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.46 |
| ▸ | FYN | P06241 | 1/20 | 0.45 |
| ▸ | LPL | P06858 | 1/20 | 0.44 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7448864 | 1.00 | CYP2A6 (0.58) | CYP2A6CYP2E1CYP2B6ESR1ESR2 | |
| SCHEMBL28764321 | 0.98 | CYP2A6 (0.56) | CYP2A6CYP2E1CYP2B6ESR1ESR2 | |
| SCHEMBL14542299 | 0.88 | ESR2 (0.54) | CYP2A6CYP2E1CYP2B6ESR1ESR2 | |
| SCHEMBL4312306 | 0.88 | CYP17A1 (0.66) | CYP2A6CYP2E1CYP2B6ESR1ESR2 | |
| SCHEMBL27989815 | 0.87 | CYP2A6 (0.74) | CYP2A6CYP2E1CYP2B6ACMSDERN1 | |
| SCHEMBL2125063 | 0.81 | CYP2A6 (0.72) | CYP2A6CYP2E1CYP2B6ACMSDERN1 | |
| SCHEMBL13210803 | 0.79 | ESR1 (0.61) | CYP2B6ESR1ESR2ACMSDERN1 | |
| SCHEMBL6067952 | 0.78 | CYP2A6 (0.50) | CYP2A6CYP2E1CYP2B6ACMSDERN1 | |
| SCHEMBL24106775 | 0.77 | CYP2A6 (0.95) | CYP2A6CYP2E1CYP2B6ACMSDKCNH2 | |
| SCHEMBL3997707 | 0.76 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113897062-B | Heat-conducting insulating silicon rubber for 5G and preparation method thereof | 广东乐普泰新材料科技有限公司 | 2023-08-25 | — | — | CN | claimed |
| WO-2015183931-A1 | STABILIZED CHEMILUMINESCENT SYSTEM | LI-COR, INC. (US) | 2015-12-03 | — | — | WO | claimed |
| US-20150346202-A1 | STABILIZED CHEMILUMINESCENT SYSTEM | Ll-COR, INC. (US) | 2015-12-03 | — | — | US | claimed |
| CN-1308627-A | 11-Aryl-benzo[b]naphtho[2,3-d]furans and 11-aryl-aryl-benzo[b]anphtho[2,3-d]thiophenes useful in the treatment of insulin resistance and hyperglycemia | AMERICAN HOME PROD (US) | 2001-08-15 | — | — | CN | claimed |
| CN-113897062-B | Heat-conducting insulating silicon rubber for 5G and preparation method thereof | 广东乐普泰新材料科技有限公司 | 2023-08-25 | — | — | CN | disclosed |
| CN-113897062-A | Heat-conducting insulating silicon rubber for 5G and preparation method thereof | 广东乐普泰新材料科技有限公司 | 2022-01-07 | — | — | CN | disclosed |
| EP-2259377-B1 | SOLAR CELL | SHARP KK (JP) | 2020-06-03 | — | — | EP | disclosed |
| EP-3212694-B1 | SILANES AND SILICIC ACID (HETERO) POLYCONDENSATES SUBSTITUTED WITH AROMATIC RESIDUES AND WITH HYDROXY GROUPS, AND DERIVATIVES THEREOF, WHICH ARE SUITABLE, AS SUCH OR AS COMPOSITES, FOR (MATRIX) SYSTEMS HAVING HIGH TRANSLUCENCE AND GOOD MECHANICAL PROPERTIES | WOLTER HERBERT (DE) | 2019-03-27 | — | — | EP | disclosed |
| CN-103709153-B | Benzothiophene derivative and its application in field of organic electroluminescence | 昆山维信诺显示技术有限公司 | 2019-01-29 | — | — | CN | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | WILLIAM MARSH RICE UNIVERSITY (US) | 2018-03-01 | — | — | US | disclosed |
| EP-3268489-A1 | FLUOROGENIC AND CHROMOGENIC SUBSTRATE | LI-COR, INC. (US) | 2018-01-17 | — | — | EP | disclosed |
| US-20070078263-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-04-05 | — | — | US | disclosed |
| US-20070066820-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | DECODE CHEMISTRY, INC. (US) | 2007-03-22 | — | — | US | disclosed |
| US-20060122256-A1 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activators | GILLESPIE PAUL | 2006-06-08 | — | — | US | disclosed |
| CN-1177821-C | Matrix metalloprotease inhibitors | - | 2004-12-01 | — | — | CN | disclosed |
| CN-1160045-A | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 1997-09-24 | — | — | CN | disclosed |
| EP-0455471-A2 | Improved chemiluminescent reagents and methods | Hitachi Chemical Co., Ltd. (JP) | 1991-11-06 | — | — | EP | disclosed |
| US-4212882-A | ANTIINFLAMMATORY INTERMEDIATES | RIKER LABORATORIES, INC. (US) | 1980-07-15 | — | — | US | disclosed |
| US-4172082-A | ANTIINFLAMMATORY AGENTS | RIKER LABORATORIES, INC. (US) | 1979-10-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070066820-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | CYP2A6 247/4885CYP2E1 262/4885CYP2B6 193/4885 |
| US-20060122256-A1 | Biaryloxymethylarenecarboxylic acids as glycogen synthase activators | GYS2, GYS1, GSK3A | CYP2A6 132/4885CYP2E1 370/4885CYP2B6 238/4885 |
| US-20070078263-A1 | BIARYL SUBSTITUTED HETEROCYCLE INHIBITORS OF LTA4H FOR TREATING INFLAMMATION | LTA4H, LTB4R, LTC4S | CYP2A6 247/4885CYP2E1 262/4885CYP2B6 193/4885 |
| US-20180057444-A1 | AMINATION AND HYDROXYLATION OF ARYLMETAL COMPOUNDS | AHR, TYR, CYP1A1 | CYP2A6 14/4885CYP2E1 8/4885CYP2B6 7/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.