Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC6A9 | P48067 | 6/20 | 0.56 |
| ▸ | SLC6A5 | Q9Y345 | 3/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11533929 | 0.86 | SLC9A1 (0.56) | SLC6A9POLBSMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL9271015 | 0.82 | SLC9A1 (0.62) | SMN1; SMN2NPC1 | |
| SCHEMBL17088275 | 0.80 | CA12 (0.50) | SMN1; SMN2ALDH1A1HPGDLMNAMAPT | |
| SCHEMBL17395881 | 0.80 | NPC1 (0.68) | SLC6A9SLC6A5POLBSMN1; SMN2NPC1 | |
| Hydrochloric Acid SCHEMBL11711315 | 0.79 | HSP90AA1 (0.49) | SLC6A9SMN1; SMN2ALDH1A1HPGDLMNA | |
| SCHEMBL17407220 | 0.79 | ALDH1A1 (0.58) | SLC6A9SLC6A5POLBSMN1; SMN2NPC1 | |
| SCHEMBL4093686 | 0.79 | SMN1; SMN2 (0.61) | POLBSMN1; SMN2NPC1ALDH1A1HPGD | |
| SCHEMBL10942684 | 0.79 | MAPT (0.59) | POLBSMN1; SMN2NPC1ALDH1A1LMNA | |
| SCHEMBL6955366 | 0.77 | ALDH1A1 (0.71) | SLC6A9SLC6A5SMN1; SMN2NPC1ALDH1A1 | |
| SCHEMBL8214889 | 0.76 | ACP1 (0.43) | SLC6A9POLBALDH1A1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |