Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACP1 | P24666 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 3/20 | 0.43 |
| ▸ | CA9 | Q16790 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.43 |
| ▸ | MTOR | P42345 | 3/20 | 0.40 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.40 |
| ▸ | PRKDC | P78527 | 1/20 | 0.39 |
| ▸ | CA3 | P07451 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA6 | P23280 | 1/20 | 0.39 |
| ▸ | CA5A | P35218 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA13 | Q8N1Q1 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CA5B | Q9Y2D0 | 1/20 | 0.39 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.39 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8140957 | 0.79 | MAPT (0.53) | POLBPIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL8214404 | 0.76 | SLC6A9 (0.56) | POLBSLC6A9ALDH1A1MAPTTSHR | |
| SCHEMBL12647466 | 0.71 | POLB (0.73) | POLBMTORPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL16164314 | 0.70 | OPRK1 (0.46) | POLBPRKDCPIK3R1PIK3CAALDH1A1 | |
| SCHEMBL19211638 | 0.70 | CYP1A2 (0.54) | CA2CA9POLBCA1MTOR | |
| Hydrochloric Acid SCHEMBL988424 | 0.69 | CYP1A2 (0.52) | CA2CA9POLBCA1MTOR | |
| SCHEMBL209882 | 0.68 | ALDH1A1 (0.71) | POLBALDH1A1MAPTKMT2A | |
| SCHEMBL31283651 | 0.68 | ALDH1A1 (0.71) | POLBALDH1A1MAPTKMT2A | |
| SCHEMBL18412768 | 0.68 | ALDH1A1 (0.51) | PRKDCPIK3R1PIK3CAALDH1A1MAPT | |
| SCHEMBL18412801 | 0.68 | OPRK1 (0.60) | PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2000023444-A1 | 5,7-DISUBSTITUTED-4-AMINOPYRIDO[2,3-D]PYRIMIDINE COMPOUNDS | ABBOTT LABORATORIES (US) | 2000-04-27 | — | — | WO | disclosed |