Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 6/20 | 0.74 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | MAPT | P10636 | 2/20 | 0.65 |
| ▸ | MEN1 | O00255 | 1/20 | 0.65 |
| ▸ | RARA | P10276 | 1/20 | 0.65 |
| ▸ | MTOR | P42345 | 1/20 | 0.65 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | PLK1 | P53350 | 1/20 | 0.59 |
| ▸ | THRA | P10827 | 4/20 | 0.57 |
| ▸ | THRB | P10828 | 4/20 | 0.57 |
| ▸ | HPGD | P15428 | 1/20 | 0.55 |
| ▸ | MMP12 | P39900 | 1/20 | 0.54 |
| ▸ | MMP13 | P45452 | 1/20 | 0.54 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.52 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12243159 | 0.98 | RARB (0.72) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9075010 | 0.95 | RARB (0.75) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL967078 | 0.94 | HSD17B10 (0.67) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL7331490 | 0.93 | RARB (0.76) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9230041 | 0.93 | RARB (0.76) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL11106134 | 0.93 | RARB (0.76) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL963847 | 0.89 | THRA (0.67) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL9406602 | 0.89 | RARB (0.58) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL499485 | 0.87 | THRA (0.70) | RARBALDH1A1KMT2AMAPTMEN1 | |
| SCHEMBL965858 | 0.87 | THRA (0.70) | RARBALDH1A1KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240360107-A1 | AN EIF4A INHIBITOR WITH A NOVEL MECHANISM OF ACTION | UNIV ARIZONA (US) | 2024-10-31 | — | — | US | disclosed |
| WO-2023034813-A1 | AN EIF4A INHIBITOR WITH A NOVEL MECHANISM OF ACTION | ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA (US) | 2023-03-09 | — | — | WO | disclosed |
| US-7790744-B2 | Cyclic peptide antifungal agents and process for preparation thereof | ELI LILLY AND COMPANY (US) | 2010-09-07 | — | — | US | disclosed |
| US-6743777-B1 | TRISPHENYL ACYL DERIVATIVES OF THE ECHINOCANDIN CLASS; CANDIDA ALBICANS; ANTIFUNGAL AND ANTIPARASITIC; CYCLIC HEXAPEPTIDES HAVING UNIQUE SIDE CHAIN ACYL GROUP | ELI LILLY AND COMPANY | 2004-06-01 | — | — | US | disclosed |
| EP-1031349-A1 | Use of substituted 4-biarylbutyric and 5-biarylpentanoic acid derivatives for the treatment of cerebral diseases | Bayer Aktiengesellschaft (DE) | 2000-08-30 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240360107-A1 | AN EIF4A INHIBITOR WITH A NOVEL MECHANISM OF ACTION | EIF4A1, EIF4A2, EIF4A3 | RARB 4166/4885ALDH1A1 3348/4885KMT2A 1696/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.