Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RARB | P10826 | 7/20 | 0.75 |
| ▸ | MEN1 | O00255 | 2/20 | 0.73 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.73 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.73 |
| ▸ | RARA | P10276 | 1/20 | 0.73 |
| ▸ | MAPT | P10636 | 1/20 | 0.73 |
| ▸ | MTOR | P42345 | 1/20 | 0.73 |
| ▸ | THRA | P10827 | 8/20 | 0.61 |
| ▸ | THRB | P10828 | 8/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.59 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.55 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11106134 | 0.98 | RARB (0.76) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL7331490 | 0.98 | RARB (0.76) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL9230041 | 0.98 | RARB (0.76) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8214463 | 0.95 | RARB (0.74) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL963847 | 0.94 | THRA (0.67) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL12243159 | 0.93 | RARB (0.72) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL965858 | 0.93 | THRA (0.70) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL4185050 | 0.93 | THRA (0.70) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL8383207 | 0.93 | THRA (0.70) | RARBMEN1KMT2AALDH1A1RARA | |
| SCHEMBL499485 | 0.93 | THRA (0.70) | RARBMEN1KMT2AALDH1A1RARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | DIC CORPORATION (JP) | 2017-10-26 | — | — | US | disclosed |
| EP-0465621-B1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK PATENT GMBH (DE) | 1996-11-13 | — | — | EP | disclosed |
| EP-0107759-B1 | CYCLOHEXANE DERIVATIVES AND THEIR USE AS COMPONENTS FOR LIQUID CRYSTALS | MERCK PATENT GmbH (DE) | 1992-12-16 | — | — | EP | disclosed |
| US-5108652-A | Liquid crystal dielectrics | Merck patent Gesellschaft mit beschrankter Haftung Darmstadt (DE) | 1992-04-28 | — | — | US | disclosed |
| WO-1991011418-A1 | PARTIALLY FLUORINATED COMPOUNDS | MERCK Patent Gesellschaft mit beschränkter Haftung (DE) | 1991-08-08 | — | — | WO | disclosed |
| US-4986931-A | Cyclohexane derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1991-01-22 | — | — | US | disclosed |
| EP-0154849-B1 | CYCLOHEXANE DERIVATIVES | MERCK PATENT GmbH (DE) | 1989-01-25 | — | — | EP | disclosed |
| US-4572794-A | Acetonitriles, their preparation, and dielectrics and electro-optical display elements containing them | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1986-02-25 | — | — | US | disclosed |
| EP-0154849-A2 | Cyclohexane derivatives | MERCK PATENT GmbH (DE) | 1985-09-18 | — | — | EP | disclosed |
| US-4510069-A | LIQUID CRYSTALS | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1985-04-09 | — | — | US | disclosed |
| EP-0107759-A2 | Cyclohexane derivatives and their use as components for liquid crystals | MERCK PATENT GmbH (DE) | 1984-05-09 | — | — | EP | disclosed |
| US-4382012-A | Liquid crystalline diketones | MERCK PATENT GESELLSCHAFT MIT BESCHRAENKTER HAFTUNG (DE) | 1983-05-03 | — | — | US | disclosed |
| EP-0019060-B1 | DIKETONES, PROCESS FOR THEIR PREPARATION AND THEIR USE AS COMPONENTS OF LIQUID-CRYSTALLINE DIELECTRICS | MERCK PATENT GmbH (DE) | 1982-04-21 | — | — | EP | disclosed |
| US-4297515-A | Diketones useful as liquid crystals | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-10-27 | — | — | US | disclosed |
| EP-0019060-A1 | Diketones, process for their preparation and their use as components of liquid-crystalline dielectrics | MERCK PATENT GmbH (DE) | 1980-11-26 | — | — | EP | disclosed |
| US-4017416-A | P-cyanophenyl 4-alkyl-4'-biphenylcarboxylate, method for preparing same and liquid crystal compositions using same | CHISSO CORPORATION (JA) | 1977-04-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20170306233-A1 | POLYMERIZABLE COMPOUND AND OPTICALLY ANISOTROPIC BODY | SMC4, PHOSPHO1, SMCHD1 | RARB 3783/4885MEN1 289/4885KMT2A 3816/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.