Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | CACNA1H | O95180 | 2/20 | 0.34 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.34 |
| ▸ | CACNA1C | Q13936 | 2/20 | 0.34 |
| ▸ | XPO1 | O14980 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.33 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.33 |
| ▸ | JUN | P05412 | 1/20 | 0.32 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.32 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.32 |
| ▸ | RELA | Q04206 | 1/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.32 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2090729 | 0.78 | ALDH1A1 (0.49) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL832709 | 0.78 | ALDH1A1 (0.37) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL2093753 | 0.77 | L3MBTL1 (0.41) | ALDH1A1MEN1KMT2AXPO1TAAR1 | |
| SCHEMBL3757830 | 0.77 | CACNA1B (0.41) | ALDH1A1SMN1; SMN2MAPK1KMT2ACACNA1H | |
| SCHEMBL565623 | 0.76 | POLB (0.46) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL831077 | 0.76 | NOTUM (0.41) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL9593033 | 0.75 | ALDH1A1 (0.52) | ALDH1A1SMN1; SMN2XPO1L3MBTL1CYP1A2 | |
| SCHEMBL29021390 | 0.75 | CA1 (0.35) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL31337111 | 0.75 | CA1 (0.35) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A | |
| SCHEMBL6357726 | 0.74 | NFKB1 (0.40) | ALDH1A1SMN1; SMN2MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031501-A2 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |