Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 5/20 | 0.40 |
| ▸ | TRPV3 | Q8NET8 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | CTSA | P10619 | 2/20 | 0.39 |
| ▸ | ACMSD | Q8TDX5 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CASP3 | P42574 | 1/20 | 0.39 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.39 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.39 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.39 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.38 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | SIRT5 | Q9NXA8 | 1/20 | 0.37 |
| ▸ | DHFR | P00374 | 1/20 | 0.37 |
| ▸ | ALKBH5 | Q6P6C2 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8218291 | 0.81 | TRPV3 (0.46) | TRPV3CTSA | |
| SCHEMBL8211093 | 0.73 | KDM4E (0.39) | DHODHTRPV3KMOCTSAPTGER1 | |
| SCHEMBL8202794 | 0.73 | MPL (0.38) | DHODHTRPV3BRS3KDM4EALDH1A1 | |
| SCHEMBL8212907 | 0.72 | MTNR1A (0.37) | DHODHTRPV3ADORA2AADORA1 | |
| SCHEMBL11823508 | 0.72 | DCLRE1B (0.46) | KDM4EALDH1A1HPGD | |
| SCHEMBL21811216 | 0.71 | PARP1 (0.48) | DHODHNPC1RAB9AACMSDSIRT5 | |
| SCHEMBL8214581 | 0.71 | ERN1 (0.33) | TRPV3L3MBTL1CASP3SENP8SENP7 | |
| SCHEMBL8214589 | 0.70 | EIF4E (0.43) | DHODHTRPV3KMOCTSAKDM4E | |
| SCHEMBL31490593 | 0.69 | DHODH (0.69) | DHODHNPC1RAB9ADHFRALKBH5 | |
| SCHEMBL31212334 | 0.69 | PARP1 (0.46) | DHODHNPC1RAB9AACMSDSIRT5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2008031501-A2 | 2-PHENOXY NICOTINE ACID DERIVATIVE AND USE THEREOF | BAYER SCHERING PHARMA AKTIENGESELLSCHAFT (DE) | 2008-03-20 | — | — | WO | disclosed |