Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 3/20 | 0.32 |
| ▸ | DHFR | P00374 | 1/20 | 0.32 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.32 |
| ▸ | HTR2A | P28223 | 1/20 | 0.32 |
| ▸ | DNM1 | Q05193 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 2/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | TP53 | P04637 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.31 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8215587 | 1.00 | NPC1 (0.33) | NPC1ALDH1A1CYP19A1DHFRGPR84 | |
| SCHEMBL8215548 | 0.99 | GPR84 (0.33) | NPC1ALDH1A1CYP19A1DHFRGPR84 | |
| SCHEMBL8216453 | 0.88 | DHFR (0.32) | NPC1ALDH1A1DHFRGPR84HTR2A | |
| SCHEMBL8216356 | 0.88 | DHFR (0.32) | NPC1ALDH1A1DHFRGPR84HTR2A | |
| SCHEMBL8220095 | 0.86 | GPR84 (0.33) | DHFRGPR84HTR2ADNM1 | |
| SCHEMBL8218131 | 0.85 | NPC1 (0.32) | NPC1ALDH1A1CYP19A1DHFRHTR2A | |
| SCHEMBL8215488 | 0.85 | NPC1 (0.32) | NPC1ALDH1A1CYP19A1DHFRHTR2A | |
| SCHEMBL8216335 | 0.85 | KCNH3 (0.35) | NPC1ALDH1A1SMN1; SMN2HTT | |
| SCHEMBL8208227 | 0.84 | NPC1 (0.30) | NPC1ALDH1A1 | |
| SCHEMBL8216410 | 0.82 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6136995-A | Process for producing aminosilane compounds | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2000-10-24 | — | — | US | disclosed |